Multiomics analysis of Hemsleya ellipsoidea reveals genome evolution and specialized cucurbitacin IIa biosynthesis in a medicinal Cucurbitaceae species.

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Title: Multiomics analysis of Hemsleya ellipsoidea reveals genome evolution and specialized cucurbitacin IIa biosynthesis in a medicinal Cucurbitaceae species.
Authors: Zhao FF; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Xie GC; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Huang LM; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Chen KH; Yunnan Shanyuan Biotechnology Co., Ltd., Lincang, Yunnan 677000, China., Zhang WL; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Feng YM; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Wang ZK; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Zhang P; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Qiao ZC; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Fu CH; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China., Yu LJ; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.
Source: Horticulture research [Hortic Res] 2026 Jan 13; Vol. 13 (4), pp. uhaf363. Date of Electronic Publication: 2026 Jan 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101655540 Publication Model: eCollection Cited Medium: Print ISSN: 2662-6810 (Print) Linking ISSN: 20527276 NLM ISO Abbreviation: Hortic Res Subsets: PubMed not MEDLINE
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  Data: Multiomics analysis of Hemsleya ellipsoidea reveals genome evolution and specialized cucurbitacin IIa biosynthesis in a medicinal Cucurbitaceae species.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+FF%22">Zhao FF</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Xie+GC%22">Xie GC</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Huang+LM%22">Huang LM</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Chen+KH%22">Chen KH</searchLink>; Yunnan Shanyuan Biotechnology Co., Ltd., Lincang, Yunnan 677000, China.<br /><searchLink fieldCode="AU" term="%22Zhang+WL%22">Zhang WL</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Feng+YM%22">Feng YM</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Wang+ZK%22">Wang ZK</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Qiao+ZC%22">Qiao ZC</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Fu+CH%22">Fu CH</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.<br /><searchLink fieldCode="AU" term="%22Yu+LJ%22">Yu LJ</searchLink>; Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.; Key Laboratory of Biophysics in the Education Department; Hubei Engineering Research Centre for Dual-use Resource Development of Food and Medicine, Wuhan 430074, China.
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        Value: 10.1093/hr/uhaf363
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      – TitleFull: Multiomics analysis of Hemsleya ellipsoidea reveals genome evolution and specialized cucurbitacin IIa biosynthesis in a medicinal Cucurbitaceae species.
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              Text: 2026 Jan 13
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