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Acupuncture for amnestic mild cognitive impairment: Study protocol for a multicenter, single-blinded, long-term, randomized controlled trial.

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Title: Acupuncture for amnestic mild cognitive impairment: Study protocol for a multicenter, single-blinded, long-term, randomized controlled trial.
Authors: Zhang X; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Wang Z; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Sun M; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Bao Q; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Chen Z; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Liu Y; The West China Hospital, Chengdu, China., Wang Z; The Fourth People's Hospital of Chengdu, Chengdu, China., Ye F; The Sichuan Province People's Hospital, Chengdu, China., Yang Z; Traditional Chinese Medicine Hospital of Pidu district, Chengdu, China., Du X; The Nanchong Second People's Hospital, Nanchong, China., Zhang H; Traditional Chinese Medicine Hospital of Meishan, Meishan, China., Mou X; Chengdu First People's Hospital, Chengdu, China., He X; The Rehabilitation Hospital of Sichuan Province, Chengdu, China., Li D; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China., Wu K; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Yao J; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Zhong W; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Xu P; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Yang S; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Zhao L; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Yin Z; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China., Liang F; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.
Source: PloS one [PLoS One] 2026 Apr 20; Vol. 21 (4), pp. e0346717. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acupuncture for amnestic mild cognitive impairment: Study protocol for a multicenter, single-blinded, long-term, randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Sun+M%22">Sun M</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Bao+Q%22">Bao Q</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; The West China Hospital, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; The Fourth People's Hospital of Chengdu, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Ye+F%22">Ye F</searchLink>; The Sichuan Province People's Hospital, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Traditional Chinese Medicine Hospital of Pidu district, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Du+X%22">Du X</searchLink>; The Nanchong Second People's Hospital, Nanchong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Traditional Chinese Medicine Hospital of Meishan, Meishan, China.<br /><searchLink fieldCode="AU" term="%22Mou+X%22">Mou X</searchLink>; Chengdu First People's Hospital, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; The Rehabilitation Hospital of Sichuan Province, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wu+K%22">Wu K</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Yao+J%22">Yao J</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Zhong+W%22">Zhong W</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Xu+P%22">Xu P</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Liang+F%22">Liang F</searchLink>; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Apr 20; Vol. 21 (4), pp. e0346717. <i>Date of Electronic Publication: </i>2026 Apr 20 (<i>Print Publication: </i>2026).
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