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Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking.

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Title: Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking.
Authors: Bosch JA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. jabosch@genetics.utah.edu.; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA. jabosch@genetics.utah.edu., Beltran PMJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Cavers C; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., LaGraff JT; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Melanson R; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Singh A; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Chen W; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Hu Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Tattikota SG; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Liu Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Hashmi Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Asara JM; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Branon T; Departments of Genetics, Biology, and by courtesy, Chemistry, Stanford University, Stanford, CA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Ting AY; Departments of Genetics, Biology, and by courtesy, Chemistry, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Perrimon N; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. perrimon@genetics.med.harvard.edu.; Howard Hughes Medical Institute, Boston, MA, USA. perrimon@genetics.med.harvard.edu.
Source: Nature communications [Nat Commun] 2026 Apr 20; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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