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Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1.

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Title: Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1.
Authors: Campbell KM; University of California, Los Angeles Los Angeles, CA United States., Chen DG; University of California, Los Angeles Los Angeles, CA United States., Bustami ZE; Columbia University New York, NY United States., Naser Al Deen N; University of California, Los Angeles Los Angeles, CA United States., Medina E; University of California, Los Angeles Los Angeles, CA United States., Gonzalez CR; University of California, Los Angeles Los Angeles, CA United States., Maxey J; Parker Institute for Cancer Immunotherapy San Francisco, CA United States., Thompson MA; Parker Institute for Cancer Immunotherapy San Francisco, CA United States., Samorodnitsky S; Fred Hutchinson Cancer Center Seattle, WA United States., Kuklinski LF; University of California, Los Angeles Los Angeles, CA United States., Perez Garcilazo I; University of California, Los Angeles Los Angeles, CA United States., Baselga-Carretero I; University of California, Los Angeles Los Angeles, CA United States., Vega-Crespo A; University of California, Los Angeles Los Angeles, CA United States., Chen JM; University of California, Los Angeles United States., Elumalai R; Agilent Technologies (United States) Santa Clara, CA United States., Visitacion M; Agilent Technologies (United States) Santa Clara, CA United States., Schiemann R; Parker Institute for Cancer Immunotherapy San Francisco, CA United States., Padron L; Parker Institute for Cancer Immunotherapy San Francisco, CA United States., Chang C; University of California, Los Angeles Los Angeles, CA United States., Zelin AE; University of California, Los Angeles Los Angeles, CA United States., Chelluri SS; University of California, Los Angeles Los Angeles, CA United States., Boffo S; Bristol-Myers Squibb (United States) Lawrenceville, NJ United States., Kendra KL; The Ohio State University Columbus, Ohio United States., Chmielowski B; University of California, Los Angeles Los Angeles, CA United States., Truong TG; Kaiser Permanente Vallejo Medical Center Vallejo, CA United States., Khushalani NI; Moffitt Cancer Center Tampa, FL United States., Collichio F; UNC Lineberger Comprehensive Cancer Center Chapel Hill, NC United States., Ikeguchi AP; The University of Texas MD Anderson Cancer Center Houston, TX United States., Victor AI; University of Rochester Rochester, NY United States., Margolin KA; Saint John's Cancer Institute, Providence Saint John's Health Center Santa Monica, United States (+1) United States., Johnson DB; Vanderbilt University Medical Center Nashville, TN United States., Chen Y; Michigan Cancer Research Consortium Grand Rapids, MI United States., Sosman JA; Robert H. Lurie Comprehensive Cancer Center of Northwestern University Chicago, IL United States., Patel SP; University of Colorado Anschutz Medical Campus Aurora United States., Hu-Lieskovan S; University of Utah Health Care Salt Lake City, Utah United States., Moon J; Fred Hutchinson Cancer Center United States., Wells DK; Parker Institute for Cancer Immunotherapy San Francisco, CA United States., Spencer CN; Rare Cancer Research Foundation Housotn, TX United States., Bellasea S; Fred Hutchinson Cancer Center Seattle, WA United States., Vanderwalde AM; Caris Life Sciences (United States) Los Angeles, CA United States., Wu MC; Fred Hutchinson Cancer Center Seattle, WA United States., Scumpia PO; University of California, Los Angeles Los Angeles, Ca United States., Ribas A; University of California, Los Angeles Los Angeles, CA United States.
Source: Cancer discovery [Cancer Discov] 2026 Apr 21. Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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IllustrationInfo
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  Data: Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1.
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Lurie Comprehensive Cancer Center of Northwestern University Chicago, IL United States.<br /><searchLink fieldCode="AU" term="%22Patel+SP%22">Patel SP</searchLink>; University of Colorado Anschutz Medical Campus Aurora United States.<br /><searchLink fieldCode="AU" term="%22Hu-Lieskovan+S%22">Hu-Lieskovan S</searchLink>; University of Utah Health Care Salt Lake City, Utah United States.<br /><searchLink fieldCode="AU" term="%22Moon+J%22">Moon J</searchLink>; Fred Hutchinson Cancer Center United States.<br /><searchLink fieldCode="AU" term="%22Wells+DK%22">Wells DK</searchLink>; Parker Institute for Cancer Immunotherapy San Francisco, CA United States.<br /><searchLink fieldCode="AU" term="%22Spencer+CN%22">Spencer CN</searchLink>; Rare Cancer Research Foundation Housotn, TX United States.<br /><searchLink fieldCode="AU" term="%22Bellasea+S%22">Bellasea S</searchLink>; Fred Hutchinson Cancer Center Seattle, WA United States.<br /><searchLink fieldCode="AU" term="%22Vanderwalde+AM%22">Vanderwalde AM</searchLink>; Caris Life Sciences (United States) Los Angeles, CA United States.<br /><searchLink fieldCode="AU" term="%22Wu+MC%22">Wu MC</searchLink>; Fred Hutchinson Cancer Center Seattle, WA United States.<br /><searchLink fieldCode="AU" term="%22Scumpia+PO%22">Scumpia PO</searchLink>; University of California, Los Angeles Los Angeles, Ca United States.<br /><searchLink fieldCode="AU" term="%22Ribas+A%22">Ribas A</searchLink>; University of California, Los Angeles Los Angeles, CA United States.
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