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Sex-biased intratumoral microbiome influences tumor molecular and immune landscape and disease outcomes.

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Title: Sex-biased intratumoral microbiome influences tumor molecular and immune landscape and disease outcomes.
Authors: Shan Y; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Huang Y; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Lee A; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Elmorsi RM; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt., Phan T; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Chaudhury I; Caris Life Sciences, Irving, TX, USA., Corbiere T; Caris Life Sciences, Irving, TX, USA., Collins LB; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Hirsch EB; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA., Weinberg BA; Ruesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Johnson JM; Department of Otolaryngology - Head and Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA., Antonarakis ES; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Lou E; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA., Huang RS; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. Electronic address: rshuang@umn.edu.
Source: Cell reports. Medicine [Cell Rep Med] 2026 May 19; Vol. 7 (5), pp. 102757. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Shan+Y%22">Shan Y</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Elmorsi+RM%22">Elmorsi RM</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22Phan+T%22">Phan T</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhury+I%22">Chaudhury I</searchLink>; Caris Life Sciences, Irving, TX, USA.<br /><searchLink fieldCode="AU" term="%22Corbiere+T%22">Corbiere T</searchLink>; Caris Life Sciences, Irving, TX, USA.<br /><searchLink fieldCode="AU" term="%22Collins+LB%22">Collins LB</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hirsch+EB%22">Hirsch EB</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Weinberg+BA%22">Weinberg BA</searchLink>; Ruesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+JM%22">Johnson JM</searchLink>; Department of Otolaryngology - Head and Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Antonarakis+ES%22">Antonarakis ES</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lou+E%22">Lou E</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Huang+RS%22">Huang RS</searchLink>; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. Electronic address: rshuang@umn.edu.
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