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Combining circulating tumor cell and circulating cell-free DNA analyses broadens clinical applicability of liquid biopsy in high grade serous tubo-ovarian carcinoma.

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Title: Combining circulating tumor cell and circulating cell-free DNA analyses broadens clinical applicability of liquid biopsy in high grade serous tubo-ovarian carcinoma.
Authors: Cavina B; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., Corrà S; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., Coadă CA; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., De Luise M; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., Lemma S; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., Coluccelli S; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., De Leo A; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., Di Costanzo S; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., Mezzapesa F; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., Girolimetti G; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy., De Iaco P; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., Porcelli AM; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Perrone AM; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy., de Biase D; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna, Italy., Gasparre G; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy. giuseppe.gasparre3@unibo.it.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy. giuseppe.gasparre3@unibo.it.; Centro Studi e Ricerca sulle Neoplasie Ginecologiche, University of Bologna, Bologna, Italy. giuseppe.gasparre3@unibo.it., Kurelac I; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy. ivana.kurelac@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ivana.kurelac@unibo.it.
Source: Experimental hematology & oncology [Exp Hematol Oncol] 2026 Apr 21; Vol. 15 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Letter
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590676 Publication Model: Electronic Cited Medium: Print ISSN: 2162-3619 (Print) Linking ISSN: 21623619 NLM ISO Abbreviation: Exp Hematol Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Combining circulating tumor cell and circulating cell-free DNA analyses broadens clinical applicability of liquid biopsy in high grade serous tubo-ovarian carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Cavina+B%22">Cavina B</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Corrà+S%22">Corrà S</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Coadă+CA%22">Coadă CA</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22De+Luise+M%22">De Luise M</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Lemma+S%22">Lemma S</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Coluccelli+S%22">Coluccelli S</searchLink>; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22De+Leo+A%22">De Leo A</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Costanzo+S%22">Di Costanzo S</searchLink>; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mezzapesa+F%22">Mezzapesa F</searchLink>; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Girolimetti+G%22">Girolimetti G</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22De+Iaco+P%22">De Iaco P</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Porcelli+AM%22">Porcelli AM</searchLink>; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Perrone+AM%22">Perrone AM</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy.; Division of Gynecologic Oncology, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22de+Biase+D%22">de Biase D</searchLink>; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Bologna, Italy.; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Gasparre+G%22">Gasparre G</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy. giuseppe.gasparre3@unibo.it.; Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy. giuseppe.gasparre3@unibo.it.; Centro Studi e Ricerca sulle Neoplasie Ginecologiche, University of Bologna, Bologna, Italy. giuseppe.gasparre3@unibo.it.<br /><searchLink fieldCode="AU" term="%22Kurelac+I%22">Kurelac I</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, Bologna, Italy. ivana.kurelac@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ivana.kurelac@unibo.it.
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  Data: <searchLink fieldCode="JN" term="%22101590676%22">Experimental hematology & oncology</searchLink> [Exp Hematol Oncol] 2026 Apr 21; Vol. 15 (1). <i>Date of Electronic Publication: </i>2026 Apr 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101590676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2162-3619 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221623619%22">21623619 </searchLink><i>NLM ISO Abbreviation: </i>Exp Hematol Oncol <i>Subsets: </i>PubMed not MEDLINE
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