The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging.

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Title: The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging.
Authors: Kojima D; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Yaku K; Department of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Japan., Kosugi S; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Mitsuno R; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kaneko K; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kawano Y; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Hishikawa A; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Katoh M; Departments of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.; Department of Frontier Cardiovascular Science, The University of Tokyo, Tokyo, Japan., Satoh A; Department of Integrative Physiology, Division of Brain Science, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Japan.; Department of Integrative Physiology, Geroscience Research Center, National Center of Geriatrics and Gerontology, Obu, Japan., Toyokuni S; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan., Azegami T; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kinouchi K; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Yamaguchi S; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Itoh H; Center for Preventive Medicine, Keio University Hospital, Tokyo, Japan., Kanda T; Division of Nephrology, Department of Internal Medicine, Shimane University, Izumo, Shimane, Japan.; The Center for Integrated Kidney Research and Advance (IKRA), Faculty of Medicine, Shimane University, Izumo, Shimane, Japan., Yamauchi T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Nakagawa T; Department of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Japan., Hayashi K; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Yoshino J; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.; Division of Nephrology, Department of Internal Medicine, Shimane University, Izumo, Shimane, Japan.; The Center for Integrated Kidney Research and Advance (IKRA), Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Source: Aging cell [Aging Cell] 2026 May; Vol. 25 (5), pp. e70509.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
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  Data: The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging.
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  Data: <searchLink fieldCode="AU" term="%22Kojima+D%22">Kojima D</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yaku+K%22">Yaku K</searchLink>; Department of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Kosugi+S%22">Kosugi S</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mitsuno+R%22">Mitsuno R</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneko+K%22">Kaneko K</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawano+Y%22">Kawano Y</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hishikawa+A%22">Hishikawa A</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mizuno+S%22">Mizuno S</searchLink>; Laboratory Animal Resource Center in Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Katoh+M%22">Katoh M</searchLink>; Departments of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.; Department of Frontier Cardiovascular Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Satoh+A%22">Satoh A</searchLink>; Department of Integrative Physiology, Division of Brain Science, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Japan.; Department of Integrative Physiology, Geroscience Research Center, National Center of Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Toyokuni+S%22">Toyokuni S</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Azegami+T%22">Azegami T</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kinouchi+K%22">Kinouchi K</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+S%22">Yamaguchi S</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Itoh+H%22">Itoh H</searchLink>; Center for Preventive Medicine, Keio University Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kanda+T%22">Kanda T</searchLink>; Division of Nephrology, Department of Internal Medicine, Shimane University, Izumo, Shimane, Japan.; The Center for Integrated Kidney Research and Advance (IKRA), Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.<br /><searchLink fieldCode="AU" term="%22Yamauchi+T%22">Yamauchi T</searchLink>; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagawa+T%22">Nakagawa T</searchLink>; Department of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+K%22">Hayashi K</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshino+J%22">Yoshino J</searchLink>; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.; Division of Nephrology, Department of Internal Medicine, Shimane University, Izumo, Shimane, Japan.; The Center for Integrated Kidney Research and Advance (IKRA), Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101130839 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-9726 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214749718%22">14749718 </searchLink><i>NLM ISO Abbreviation: </i>Aging Cell <i>Subsets: </i>MEDLINE
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        Value: 10.1111/acel.70509
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              Text: 2026 May
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