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Layered Double Hydroxide-Loaded Dl-3-n-Butylphthalide Alleviates Renal Ischemia-Reperfusion Injury by Regulating the PI3K-AKT-Nrf2 Signaling Pathway.

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Title: Layered Double Hydroxide-Loaded Dl-3-n-Butylphthalide Alleviates Renal Ischemia-Reperfusion Injury by Regulating the PI3K-AKT-Nrf2 Signaling Pathway.
Authors: Yan Y; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Wang K; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Ren L; Department of Nuclear Medicine, School of Laboratory Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Ma JJ; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Zhu XC; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Ding HF; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Chu JX; School of Basic Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Zhu ZG; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Xia JY; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Xia Y; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Xu Y; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., He MH; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Wang WR; Anhui Provincial Key Laboratory of Tumor Evolution and Intelligent Diagnosis and Treatment, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Zhang CL; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.
Source: International journal of nanomedicine [Int J Nanomedicine] 2026 Apr 14; Vol. 21, pp. 594110. Date of Electronic Publication: 2026 Apr 14 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Layered Double Hydroxide-Loaded Dl-3-n-Butylphthalide Alleviates Renal Ischemia-Reperfusion Injury by Regulating the PI3K-AKT-Nrf2 Signaling Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+K%22">Wang K</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ren+L%22">Ren L</searchLink>; Department of Nuclear Medicine, School of Laboratory Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ma+JJ%22">Ma JJ</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+XC%22">Zhu XC</searchLink>; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ding+HF%22">Ding HF</searchLink>; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chu+JX%22">Chu JX</searchLink>; School of Basic Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+ZG%22">Zhu ZG</searchLink>; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xia+JY%22">Xia JY</searchLink>; School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xia+Y%22">Xia Y</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22He+MH%22">He MH</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+WR%22">Wang WR</searchLink>; Anhui Provincial Key Laboratory of Tumor Evolution and Intelligent Diagnosis and Treatment, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+CL%22">Zhang CL</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22101263847%22">International journal of nanomedicine</searchLink> [Int J Nanomedicine] 2026 Apr 14; Vol. 21, pp. 594110. <i>Date of Electronic Publication: </i>2026 Apr 14 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22DOVE+Medical+Press%22">DOVE Medical Press </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101263847 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1178-2013 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211769114%22">11769114 </searchLink><i>NLM ISO Abbreviation: </i>Int J Nanomedicine <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 14
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