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Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial.

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Title: Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial.
Authors: Baker JV; Infectious Diseases, Hennepin Healthcare, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Siegel L; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Losso M; CICAL, Fundación IBIS, Buenos Aires, Argentina.; Hospital General de Agudos Jose Maria Ramos Mejía, Buenos Aires, Argentina., Vasudeva S; Virginia Tech Carilion School of Medicine, Salem, Virginia, USA.; Department of Medicine, Salem VA Medical Center, U.S. Department of Veterans Affairs, Salem, Virginia, USA., Nordwall JA; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Harper K; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Grund B; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Havens JP; College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA., Fletcher CV; Antiviral Pharmacology Laboratory, University of Nebraska Medical Center, Omaha, Nebraska, USA., Fishchuk R; Central City Clinical Hospital of Ivano-Frankivsk City Council, Ivano-Frankivsk, Ukraine., Kobrynska O; Central City Clinical Hospital of Ivano-Frankivsk City Council, Ivano-Frankivsk, Ukraine., Abutidze A; T. Tsertsvadze Infectious Diseases, AIDS and Clinical Immunology Research Center, Tbilisi, Georgia., Metchurtchlishvili R; T. Tsertsvadze Infectious Diseases, AIDS and Clinical Immunology Research Center, Tbilisi, Georgia., Ginde A; Department of Emergency Medicine, University of Colorado Anschutz, School of Medicine, Aurora, Colorado, USA., Aggarwal NR; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Poulakou G; National and Kapodistrian University of Athens, Medical School, Athens, Greece., Mourad A; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Gibbs K; Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Saito S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Society, Toyama, Shinjuku-ku, Tokyo, Japan., Chayakulkeeree M; Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Mootsikapun P; Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand., Honda H; Department of Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Nagoya, Japan., Mateu L; Department of Infectious Diseases, Hospital Germans Trias i Pujol, Fundacio Lluita contra les Infeccions, Badalona, Spain., Gyrina O; Treatment and Diagnostic Center ADONIS Plus, Kyiv, Ukraine., Garcia A; University of Texas Southwestern Medical Center, Dallas, Texas, USA., Lee DG; Division of Infectious Diseases, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Casey JD; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville Tennessee, USA.; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville Tennessee, USA., Jain MK; University of Texas Southwestern, Parkland Health, Dallas, Texas, USA., Bengtson CD; Division of Pulmonary Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Hite RD; University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Hiranburana N; HIV-NAT, Thai Red Cross AIDS and Infectious Diseases Research Centre, Bangkok, Thailand.; Center of Excellence in Tuberculosis, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Matthay M; Cardiovascular Research Institute, Departments of Medicine and Anesthesia, University of California, San Francisco, San Francisco, California, USA., Arizmendez N; Intermountain Health, University of Utah School of Medicine, Murray, Utah, USA., Nguyen HH; VA Northern California Health Care System, UC Davis Health, Sacramento, California, USA., Drelick A; New York Presbyterian Weill Cornell Medical Center, New York, New York, USA., Mena Lora AJ; University of Illinois Chicago, Chicago, Illinois, USA., Parnia S; New York University Grossman School of Medicine, New York, New York, USA., Trautner BW; Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA., Portsmouth SD; Shionogi Inc., Florham Park, New Jersey, USA., Shimizu R; Shionogi & Co., Ltd., Osaka, Japan., Uehara T; Drug Development and Regulatory Division, Shionogi & Co., Ltd., Osaka, Japan., Paredes R; Department of Infectious Diseases & irsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain., Goodman A; MRC Clinical Trials Unit at University College London, London, United Kingdom.; Department of Infection at Guy's and St. Thomas' Hospital and King's College London, London, United Kingdom., Vock DM; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Gelijns AC; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Weintrob AC; Washington, DC Veteran Affairs Medical Center, Washington, DC, USA., Bajema KL; Veterans Affairs Portland Health Care System, Portland, Oregon, USA.; Division of Infectious Diseases, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA., Pett SL; MRC Clinical Trials Unit at University College London, London, United Kingdom., Lundgren J; Department of Infectious Diseases, Centre of Excellence in Health Immunity and Infection, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Schechner AJ; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Higgs ES; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Lane HC; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Matthews GV; Kirby Institute, University of New South Wales, Sydney, Australia., Self WH; Vanderbilt Institute for Clinical and Translational Research Nashville, Vanderbilt University Medical Center, Tennessee, USA.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Reilly C; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Apr 22. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
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  Data: Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial.
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              Value: 1537-6591
          Titles:
            – TitleFull: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
              Type: main
ResultId 1