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Expansion of stemlike HIV-specific CD8+ T cells and limited viral epitope diversity characterize durable posttreatment control of HIV.

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Title: Expansion of stemlike HIV-specific CD8+ T cells and limited viral epitope diversity characterize durable posttreatment control of HIV.
Authors: Crain CR; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA., Alrubayyi A; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA., Muzhingi I; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA., Traunbauer A; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA., Jeon E; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA., Deo R; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Deligiannidis EA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Shrestha P; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Etemad B; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., MacLeod H; Accelivir Diagnostics, Baltimore, MD 21202, USA., Laird GM; Accelivir Diagnostics, Baltimore, MD 21202, USA., Choudhary MC; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Peluso MJ; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Deeks SG; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Rutishauser RL; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Li JZ; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Gaiha GD; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.; Program in Health Sciences and Technology, Harvard Medical School, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Apr 22; Vol. 18 (846), pp. eaed0042. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Expansion of stemlike HIV-specific CD8<superscript>+</superscript> T cells and limited viral epitope diversity characterize durable posttreatment control of HIV.
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  Data: <searchLink fieldCode="AU" term="%22Crain+CR%22">Crain CR</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Alrubayyi+A%22">Alrubayyi A</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Muzhingi+I%22">Muzhingi I</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Traunbauer+A%22">Traunbauer A</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Jeon+E%22">Jeon E</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Deo+R%22">Deo R</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Deligiannidis+EA%22">Deligiannidis EA</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Shrestha+P%22">Shrestha P</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Etemad+B%22">Etemad B</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22MacLeod+H%22">MacLeod H</searchLink>; Accelivir Diagnostics, Baltimore, MD 21202, USA.<br /><searchLink fieldCode="AU" term="%22Laird+GM%22">Laird GM</searchLink>; Accelivir Diagnostics, Baltimore, MD 21202, USA.<br /><searchLink fieldCode="AU" term="%22Choudhary+MC%22">Choudhary MC</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Peluso+MJ%22">Peluso MJ</searchLink>; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Deeks+SG%22">Deeks SG</searchLink>; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Rutishauser+RL%22">Rutishauser RL</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Li+JZ%22">Li JZ</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Gaiha+GD%22">Gaiha GD</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.; Program in Health Sciences and Technology, Harvard Medical School, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Apr 22; Vol. 18 (846), pp. eaed0042. <i>Date of Electronic Publication: </i>2026 Apr 22.
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