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Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload.

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Title: Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload.
Authors: Yang Q; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China., Li Q; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China., Xia Y; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China., Ge J; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China., Xie Y; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China., Shen C; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China., Chen K; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China., Chen J; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China., Shen Y; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China. Electronic address: idrshen@zju.edu.cn., Tong J; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China. Electronic address: idrtong@zju.edu.cn., Zhou H; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China. Electronic address: zjnbzhd@126.com.
Source: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2026 May; Vol. 316, pp. 120150. Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China.<br /><searchLink fieldCode="AU" term="%22Xia+Y%22">Xia Y</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Ge+J%22">Ge J</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Shen+C%22">Shen C</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China. Electronic address: idrshen@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tong+J%22">Tong J</searchLink>; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China. Electronic address: idrtong@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315040, China. Electronic address: zjnbzhd@126.com.
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  Data: <searchLink fieldCode="JN" term="%227805381%22">Ecotoxicology and environmental safety</searchLink> [Ecotoxicol Environ Saf] 2026 May; Vol. 316, pp. 120150. <i>Date of Electronic Publication: </i>2026 Apr 21.
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              Text: 2026 May
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