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Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.

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Title: Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.
Authors: Ritoux A; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom., Grundy LJ; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom., Manjappa P; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Paine LW; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom., Neisen J; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Linley JE; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Smith ESJ; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.
Source: Pain reports [Pain Rep] 2026 Apr 20; Vol. 11 (3), pp. e1446. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101683899 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-2531 (Electronic) Linking ISSN: 24712531 NLM ISO Abbreviation: Pain Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.
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  Data: <searchLink fieldCode="AU" term="%22Ritoux+A%22">Ritoux A</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Grundy+LJ%22">Grundy LJ</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Manjappa+P%22">Manjappa P</searchLink>; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Paine+LW%22">Paine LW</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Neisen+J%22">Neisen J</searchLink>; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Linley+JE%22">Linley JE</searchLink>; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Smith+ESJ%22">Smith ESJ</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101683899%22">Pain reports</searchLink> [Pain Rep] 2026 Apr 20; Vol. 11 (3), pp. e1446. <i>Date of Electronic Publication: </i>2026 Apr 20 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer%22">Wolters Kluwer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101683899 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2471-2531 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224712531%22">24712531 </searchLink><i>NLM ISO Abbreviation: </i>Pain Rep <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Apr 20
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