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Cav3.1 is a neuronal leucine sensor that mediates satiety and weight loss in response to dietary protein.

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Title: Cav3.1 is a neuronal leucine sensor that mediates satiety and weight loss in response to dietary protein.
Authors: Tsang AH; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Heeley N; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Alcaino C; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Hwang E; Department of Internal Medicine, Center for Hypothalamic Research, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA., Lam BY; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Rahman T; Department of Pharmacology, University of Cambridge, Cambridge, UK., Darwish T; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Nuzzaci D; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Kay RG; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Sarkar A; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Wang R; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Basha N; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Punnoose A; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Kirwan P; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Ma M; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Yeo GS; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Merkle FT; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Gribble FM; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Reinmann F; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK., Williams KW; Department of Internal Medicine, Center for Hypothalamic Research, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA., Blouet C; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK. Electronic address: csb69@cam.ac.uk.
Source: Cell metabolism [Cell Metab] 2026 May 05; Vol. 38 (5), pp. 876-890.e13. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
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  Data: Cav3.1 is a neuronal leucine sensor that mediates satiety and weight loss in response to dietary protein.
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  Data: <searchLink fieldCode="AU" term="%22Tsang+AH%22">Tsang AH</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Heeley+N%22">Heeley N</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Alcaino+C%22">Alcaino C</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hwang+E%22">Hwang E</searchLink>; Department of Internal Medicine, Center for Hypothalamic Research, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lam+BY%22">Lam BY</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Rahman+T%22">Rahman T</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Darwish+T%22">Darwish T</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Nuzzaci+D%22">Nuzzaci D</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kay+RG%22">Kay RG</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sarkar+A%22">Sarkar A</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Basha+N%22">Basha N</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Punnoose+A%22">Punnoose A</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kirwan+P%22">Kirwan P</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ma+M%22">Ma M</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Yeo+GS%22">Yeo GS</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Merkle+FT%22">Merkle FT</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gribble+FM%22">Gribble FM</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Reinmann+F%22">Reinmann F</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Williams+KW%22">Williams KW</searchLink>; Department of Internal Medicine, Center for Hypothalamic Research, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Blouet+C%22">Blouet C</searchLink>; Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK. Electronic address: csb69@cam.ac.uk.
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