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Breaking the "Industrial Vitamin" Paradigm: La-N4 Single-Atom Sites Enable Highly Active Multicomponent Electrochemical Sensing in Tear Fluid.

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Title: Breaking the "Industrial Vitamin" Paradigm: La-N4 Single-Atom Sites Enable Highly Active Multicomponent Electrochemical Sensing in Tear Fluid.
Authors: Zhao R; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Wu Z; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Chen D; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Shen Y; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Qin X; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Zhao M; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Yan L; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China., Liu Y; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
Source: Inorganic chemistry [Inorg Chem] 2026 May 11; Vol. 65 (18), pp. 9987-9995. Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Breaking the "Industrial Vitamin" Paradigm: La-N<subscript>4</subscript> Single-Atom Sites Enable Highly Active Multicomponent Electrochemical Sensing in Tear Fluid.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+R%22">Zhao R</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Qin+X%22">Qin X</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Laboratory of Novel Optoelectronic Technology for Ophthalmic Devices (NOTOD), School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, China.; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
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  Data: <searchLink fieldCode="JN" term="%220366543%22">Inorganic chemistry</searchLink> [Inorg Chem] 2026 May 11; Vol. 65 (18), pp. 9987-9995. <i>Date of Electronic Publication: </i>2026 Apr 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0366543 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-510X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200201669%22">00201669 </searchLink><i>NLM ISO Abbreviation: </i>Inorg Chem <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1021/acs.inorgchem.6c00479
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      – Code: eng
        Text: English
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        StartPage: 9987
    Titles:
      – TitleFull: Breaking the "Industrial Vitamin" Paradigm: La-N4 Single-Atom Sites Enable Highly Active Multicomponent Electrochemical Sensing in Tear Fluid.
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          Name:
            NameFull: Zhao R
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          Name:
            NameFull: Wu Z
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            NameFull: Chen D
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            NameFull: Shen Y
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            NameFull: Zhao M
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            NameFull: Yan L
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            – D: 11
              M: 05
              Text: 2026 May 11
              Type: published
              Y: 2026
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              Value: 65
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              Value: 18
          Titles:
            – TitleFull: Inorganic chemistry
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