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Towards adaptive bioelectronic wound therapy with integrated real-time diagnostics and machine learning-driven closed-loop control.

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Title: Towards adaptive bioelectronic wound therapy with integrated real-time diagnostics and machine learning-driven closed-loop control.
Authors: Li H; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Yang HY; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA., Lu F; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA., Hee WS; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Asefifeyzabadi N; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Baniya P; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Gallegos A; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA., Schorger K; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Zhu K; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA., Recendez C; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA., Tebyani M; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Kesapragada M; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA., Keller G; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Kim S; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Luka G; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Zlobina K; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA., Nguyen T; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Figuerres S; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Franco C; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Devarajan K; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Barbee A; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Lin K; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA., Clayton SM; Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, CA, USA., Eaton A; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Aslankoohi E; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA., Soulika AM; Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, CA, USA., Zhao M; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA. minzhao@ucdavis.edu.; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA. minzhao@ucdavis.edu., Teodorescu M; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA. mteodore@ucsc.edu.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, USA. mteodore@ucsc.edu.; Genomics Institute, University of California Santa Cruz, Santa Cruz, USA. mteodore@ucsc.edu., Gomez M; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA. mgomez26@ucsc.edu., Isseroff RR; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA. rrisseroff@ucdavis.edu., Rolandi M; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA. mrolandi@ucsc.edu.; Genomics Institute, University of California Santa Cruz, Santa Cruz, USA. mrolandi@ucsc.edu.
Source: Npj biomedical innovations [NPJ Biomed Innov] 2025 Sep 23; Vol. 2 (1). Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918994495106676 Publication Model: Electronic Cited Medium: Internet ISSN: 3005-1444 (Electronic) Linking ISSN: 30051444 NLM ISO Abbreviation: NPJ Biomed Innov Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+HY%22">Yang HY</searchLink>; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+F%22">Lu F</searchLink>; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hee+WS%22">Hee WS</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Asefifeyzabadi+N%22">Asefifeyzabadi N</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Baniya+P%22">Baniya P</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gallegos+A%22">Gallegos A</searchLink>; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schorger+K%22">Schorger K</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+K%22">Zhu K</searchLink>; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Recendez+C%22">Recendez C</searchLink>; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tebyani+M%22">Tebyani M</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kesapragada+M%22">Kesapragada M</searchLink>; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Keller+G%22">Keller G</searchLink>; 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Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Devarajan+K%22">Devarajan K</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Barbee+A%22">Barbee A</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+K%22">Lin K</searchLink>; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Clayton+SM%22">Clayton SM</searchLink>; Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eaton+A%22">Eaton A</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Aslankoohi+E%22">Aslankoohi E</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Soulika+AM%22">Soulika AM</searchLink>; Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA. minzhao@ucdavis.edu.; Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA, USA. minzhao@ucdavis.edu.<br /><searchLink fieldCode="AU" term="%22Teodorescu+M%22">Teodorescu M</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA. mteodore@ucsc.edu.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, USA. mteodore@ucsc.edu.; Genomics Institute, University of California Santa Cruz, Santa Cruz, USA. mteodore@ucsc.edu.<br /><searchLink fieldCode="AU" term="%22Gomez+M%22">Gomez M</searchLink>; Department of Applied Mathematics, University of California Santa Cruz, Santa Cruz, CA, USA. mgomez26@ucsc.edu.<br /><searchLink fieldCode="AU" term="%22Isseroff+RR%22">Isseroff RR</searchLink>; Department of Dermatology, School of Medicine, University of California Davis, Davis, CA, USA. rrisseroff@ucdavis.edu.<br /><searchLink fieldCode="AU" term="%22Rolandi+M%22">Rolandi M</searchLink>; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA. mrolandi@ucsc.edu.; Genomics Institute, University of California Santa Cruz, Santa Cruz, USA. mrolandi@ucsc.edu.
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