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Complement C3aR deletion does not attenuate degeneration in a tauopathy model or alter acute inflammation-induced gene expression changes.

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Title: Complement C3aR deletion does not attenuate degeneration in a tauopathy model or alter acute inflammation-induced gene expression changes.
Authors: Wang Y; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA., Pandey S; Genentech Computational Sciences, Genentech Inc., South San Francisco, CA 94080, USA., Weber M; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA., Choy MK; Department of Translational Imaging, Genentech Inc., South San Francisco, CA 94080, USA., Wu T; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA., Chernov-Rogan T; Department of Biochemical and Cellular Physiology, Genentech Inc., South San Francisco, CA 94080, USA., Adrian M; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA., Tsai MC; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA., Ngu H; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA., Foreman O; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA., Xie L; Department of Translational Imaging, Genentech Inc., South San Francisco, CA 94080, USA., Hanson JE; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: hanson.jesse@gene.com.
Source: Cell reports [Cell Rep] 2026 May 26; Vol. 45 (5), pp. 117313. Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Complement C3aR deletion does not attenuate degeneration in a tauopathy model or alter acute inflammation-induced gene expression changes.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+S%22">Pandey S</searchLink>; Genentech Computational Sciences, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Weber+M%22">Weber M</searchLink>; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Choy+MK%22">Choy MK</searchLink>; Department of Translational Imaging, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Chernov-Rogan+T%22">Chernov-Rogan T</searchLink>; Department of Biochemical and Cellular Physiology, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Adrian+M%22">Adrian M</searchLink>; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+MC%22">Tsai MC</searchLink>; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Ngu+H%22">Ngu H</searchLink>; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Foreman+O%22">Foreman O</searchLink>; Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink>; Department of Translational Imaging, Genentech Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hanson+JE%22">Hanson JE</searchLink>; Department of Neuroscience, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: hanson.jesse@gene.com.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 May 26; Vol. 45 (5), pp. 117313. <i>Date of Electronic Publication: </i>2026 Apr 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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              Text: 2026 May 26
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