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Advanced treatment for articular cartilage lesions: Development of an injectable glucosinolate-releasing hyaluronic acid.

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Title: Advanced treatment for articular cartilage lesions: Development of an injectable glucosinolate-releasing hyaluronic acid.
Authors: Gambari L; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy., Velino C; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy., Gotti R; Department of Pharmacy and Biotechnology FABIT, University of Bologna, via Belmeloro 6, 40126, Bologna, Italy., Di Lisa L; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy., Ferrazzano L; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy., Corbisiero D; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy., Tolomelli A; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy., Panciera A; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy., Faldini C; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy., Ruffilli A; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy., D'Alessandro M; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy., Grigolo B; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy., Gualandi C; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy; Interdepartmental Center for Industrial Research on Advanced Applications in Mechanical Engineering and Materials Technology, CIRI-MAM, University of Bologna, Viale Risorgimento, 2, 40136, Bologna, Italy. Electronic address: c.gualandi@unibo.it., Desando G; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: giovanna.desando@ior.it., Focarete ML; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy; Health Sciences & Technologies (HST) CIRI, University of Bologna, Via Tolara di Sopra 41/E, 40064, Ozzano Emilia Bologna, Italy.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 May; Vol. 363, pp. 152190. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Gambari+L%22">Gambari L</searchLink>; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Velino+C%22">Velino C</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Gotti+R%22">Gotti R</searchLink>; Department of Pharmacy and Biotechnology FABIT, University of Bologna, via Belmeloro 6, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Lisa+L%22">Di Lisa L</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrazzano+L%22">Ferrazzano L</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Corbisiero+D%22">Corbisiero D</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Tolomelli+A%22">Tolomelli A</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Panciera+A%22">Panciera A</searchLink>; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Faldini+C%22">Faldini C</searchLink>; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ruffilli+A%22">Ruffilli A</searchLink>; IRCCS Istituto Ortopedico Rizzoli, 1(st) Orthopaedic and Traumatology Clinic, via G.C. Pupilli 1, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+M%22">D'Alessandro M</searchLink>; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Grigolo+B%22">Grigolo B</searchLink>; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Gualandi+C%22">Gualandi C</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy; Interdepartmental Center for Industrial Research on Advanced Applications in Mechanical Engineering and Materials Technology, CIRI-MAM, University of Bologna, Viale Risorgimento, 2, 40136, Bologna, Italy. Electronic address: c.gualandi@unibo.it.<br /><searchLink fieldCode="AU" term="%22Desando+G%22">Desando G</searchLink>; IRCCS Istituto Ortopedico Rizzoli, Laboratorio RAMSES, via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: giovanna.desando@ior.it.<br /><searchLink fieldCode="AU" term="%22Focarete+ML%22">Focarete ML</searchLink>; Department of Chemistry 'G. Ciamician' and INSTM UdR of Bologna, University of Bologna, via Gobetti 85, 40129, Bologna, Italy; Health Sciences & Technologies (HST) CIRI, University of Bologna, Via Tolara di Sopra 41/E, 40064, Ozzano Emilia Bologna, Italy.
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