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New histopathological terminology for well-differentiated hepatocellular lesions in unusual clinico-pathological scenarios: HCA-like and FNH-like.

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Title: New histopathological terminology for well-differentiated hepatocellular lesions in unusual clinico-pathological scenarios: HCA-like and FNH-like.
Authors: Sempoux C; Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. Electronic address: christine.sempoux@chuv.ch., Alves VA; Department of Pathology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil., Arola J; Department of Pathology, Helsinki University Hospital, Diagnostic Centre, and Faculty of Medicine, University of Helsinki, Helsinki, Finland., Balabaud C; Inserm, U1053, Bordeaux University, Bordeaux, France., Bioulac-Sage P; Inserm, U1053, Bordeaux University, Bordeaux, France., Colombari R; Department of Pathology, San Bonifacio Hospital, Verona, Italy., Crawford JM; Northwell Health, Department of Pathology and Laboratory Medicine, New Hyde Park, NY, USA., Dhillon AP; Department of Cellular Pathology, UCL Medical School, London, UK., di Tommaso L; Pathology Unit, IRCCS Humanitas Research Hospital, and Department of Biomedical Sciences, Humanitas University, Milan, Italy., Ferrell LD; Department of Pathology, University of California, San Francisco, CA, USA., Gill RM; Department of Pathology, University of California, San Francisco, CA, USA., Guido M; Department of Medicine-DIMED, Pathology Unit, University of Padova, Padova, Italy., Hameed B; Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Harada K; Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan., Hytiroglou P; Department of Pathology, Aristotle University Medical School, Thessaloniki, Greece., Nakanuma Y; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan, Department of Diagnostic Pathology, Fukui Prefecture Saiseikai Hospital, Fukui, Japan., Paradis V; AP-HP, Hôpital Beaujon, Department of Pathology and Université Paris-Cité, Inserm UMR 1149, Clichy, France., Rautou PE; AP-HP, Hôpital Beaujon, Department of Hepatology and Université Paris-Cité, Inserm UMR 1149, Clichy, France., Theise ND; Department of Pathology, New York University School of Medicine, New York, NY, USA., Thung S; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tsui WM; Department of Pathology, Caritas Medical Centre, Hong Kong., Snover D; Department of Pathology, Fairview Southdale Hospital, Edina, MN, USA., Stueck A; Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada., Suriawinata A; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, 03756, USA., van Leeuwen DJ; Section of Gastroenterology and Hepatology, Geisel School of Medicine at Dartmouth College, Hanover, NH 03755, USA., Quaglia A; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK. Electronic address: alberto.quaglia@nhs.net.
Corporate Authors: International Liver Pathology Study Group
Source: JHEP reports : innovation in hepatology [JHEP Rep] 2026 May; Vol. 8 (5), pp. 101778. Date of Electronic Publication: 2026 Feb 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: In Process
Database: MEDLINE Ultimate
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  Data: New histopathological terminology for well-differentiated hepatocellular lesions in unusual clinico-pathological scenarios: HCA-like and FNH-like.
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  Data: <searchLink fieldCode="AU" term="%22Sempoux+C%22">Sempoux C</searchLink>; Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. Electronic address: christine.sempoux@chuv.ch.<br /><searchLink fieldCode="AU" term="%22Alves+VA%22">Alves VA</searchLink>; Department of Pathology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Arola+J%22">Arola J</searchLink>; Department of Pathology, Helsinki University Hospital, Diagnostic Centre, and Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Balabaud+C%22">Balabaud C</searchLink>; Inserm, U1053, Bordeaux University, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Bioulac-Sage+P%22">Bioulac-Sage P</searchLink>; Inserm, U1053, Bordeaux University, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Colombari+R%22">Colombari R</searchLink>; Department of Pathology, San Bonifacio Hospital, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Crawford+JM%22">Crawford JM</searchLink>; Northwell Health, Department of Pathology and Laboratory Medicine, New Hyde Park, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dhillon+AP%22">Dhillon AP</searchLink>; Department of Cellular Pathology, UCL Medical School, London, UK.<br /><searchLink fieldCode="AU" term="%22di+Tommaso+L%22">di Tommaso L</searchLink>; Pathology Unit, IRCCS Humanitas Research Hospital, and Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrell+LD%22">Ferrell LD</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gill+RM%22">Gill RM</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guido+M%22">Guido M</searchLink>; Department of Medicine-DIMED, Pathology Unit, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Hameed+B%22">Hameed B</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Harada+K%22">Harada K</searchLink>; Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hytiroglou+P%22">Hytiroglou P</searchLink>; Department of Pathology, Aristotle University Medical School, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Nakanuma+Y%22">Nakanuma Y</searchLink>; Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan, Department of Diagnostic Pathology, Fukui Prefecture Saiseikai Hospital, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Paradis+V%22">Paradis V</searchLink>; AP-HP, Hôpital Beaujon, Department of Pathology and Université Paris-Cité, Inserm UMR 1149, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Rautou+PE%22">Rautou PE</searchLink>; AP-HP, Hôpital Beaujon, Department of Hepatology and Université Paris-Cité, Inserm UMR 1149, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Theise+ND%22">Theise ND</searchLink>; Department of Pathology, New York University School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Thung+S%22">Thung S</searchLink>; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tsui+WM%22">Tsui WM</searchLink>; Department of Pathology, Caritas Medical Centre, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Snover+D%22">Snover D</searchLink>; Department of Pathology, Fairview Southdale Hospital, Edina, MN, USA.<br /><searchLink fieldCode="AU" term="%22Stueck+A%22">Stueck A</searchLink>; Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.<br /><searchLink fieldCode="AU" term="%22Suriawinata+A%22">Suriawinata A</searchLink>; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, 03756, USA.<br /><searchLink fieldCode="AU" term="%22van+Leeuwen+DJ%22">van Leeuwen DJ</searchLink>; Section of Gastroenterology and Hepatology, Geisel School of Medicine at Dartmouth College, Hanover, NH 03755, USA.<br /><searchLink fieldCode="AU" term="%22Quaglia+A%22">Quaglia A</searchLink>; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK. Electronic address: alberto.quaglia@nhs.net.
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