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Single injection of modified self-amplifying RNA encoding a CD19 bispecific T cell engager mediates long-term malignant B cell clearance.

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Title: Single injection of modified self-amplifying RNA encoding a CD19 bispecific T cell engager mediates long-term malignant B cell clearance.
Authors: Li K; Department of Biomedical Engineering, Boston University, Boston, MA, USA., McGee JE; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Biological Design Center, Boston University, Boston, MA, USA., Wong WW; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Biological Design Center, Boston University, Boston, MA, USA., Grinstaff MW; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Department of Chemistry, Boston University, Boston, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 19. Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42039561
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Single injection of modified self-amplifying RNA encoding a CD19 bispecific T cell engager mediates long-term malignant B cell clearance.
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  Data: <searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; Department of Biomedical Engineering, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McGee+JE%22">McGee JE</searchLink>; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Biological Design Center, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wong+WW%22">Wong WW</searchLink>; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Biological Design Center, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Grinstaff+MW%22">Grinstaff MW</searchLink>; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Department of Chemistry, Boston University, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Apr 19. <i>Date of Electronic Publication: </i>2026 Apr 19.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42039561
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.64898/2026.04.18.719371
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Single injection of modified self-amplifying RNA encoding a CD19 bispecific T cell engager mediates long-term malignant B cell clearance.
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            NameFull: Li K
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            NameFull: McGee JE
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            – D: 19
              M: 04
              Text: 2026 Apr 19
              Type: published
              Y: 2026
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              Value: 2692-8205
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