Total versus subtotal gastrectomy following neoadjuvant flot chemotherapy for distal diffuse gastric adenocarcinoma: an international cohort study.
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| Title: | Total versus subtotal gastrectomy following neoadjuvant flot chemotherapy for distal diffuse gastric adenocarcinoma: an international cohort study. |
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| Authors: | Sivakumar J; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia. sivakumar.jonathan@gmail.com.; Department of Surgery, The University of Melbourne, Parkville, Melbourne, VIC, 3000, Australia. sivakumar.jonathan@gmail.com., Wong DJ; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia., Hall K; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia.; Department of Surgery, Victorian Interventional Research and Trials Unit, University of Melbourne, Austin Precinct, Heidelberg, VIC, Australia., Lee MM; Department of Medical Oncology, Box Hill Hospital, Box Hill, VIC, Australia., Duong CP; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia., Watson DI; College of Medicine and Public Health, Flinders University, Flinders, South Australia, Australia.; Department of Surgery, Flinders Medical Centre, Flinders, South Australia, Australia., Donohoe CL; Upper Gastrointestinal Surgery Unit, St James Hospital, Dublin, Ireland., Bright T; College of Medicine and Public Health, Flinders University, Flinders, South Australia, Australia.; Department of Surgery, Flinders Medical Centre, Flinders, South Australia, Australia., Aly A; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia., Chan K; Upper Gastrointestinal Surgery Unit, Royal Brisbane and Women's Hospital, Herston, QLD, Australia., Chan DL; Upper Gastrointestinal Surgery Unit, Royal Northshore Hospital, St Leonards, New South Wales, Australia.; Northern Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia., Merrett N; Upper Gastrointestinal Surgical Unit, Bankstown-Lidcombe Hospital, Bankstown, NSW, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, Australia., Gananadha S; Upper Gastrointestinal Surgery Unit, Canberra Hospital, Canberra, Australia., Lam YH; Upper Gastrointestinal Surgery Unit, Lyell McEwin Hospital, Adelaide, South Australia, Australia., Kanhere H; Upper Gastrointestinal Surgery Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia., Smithers B; Upper Gastrointestinal Surgery Unit, Princess Alexandra Hospital, University of Queensland, Brisbane, Australia., Bozin M; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia., Read M; Upper Gastrointestinal Surgery Unit, St Vincent's Hospital, Fitzroy, VIC, Australia., Mori K; Upper Gastrointestinal Surgery Unit, Northern Hospital, Epping, VIC, Australia., Johnson MA; Upper Gastrointestinal Surgery Unit, Box Hill Hospital, Box Hill, VIC, Australia., Wong E; Upper Gastrointestinal Surgery Unit, Box Hill Hospital, Box Hill, VIC, Australia., Martin SA; Upper Gastrointestinal Surgery Unit, Monash Medical Centre, Epping, VIC, Australia.; Department of Surgery, Monash University, Melbourne, VIC, Australia., Ooi G; Upper Gastrointestinal Surgery Unit, Monash Medical Centre, Epping, VIC, Australia.; Department of Surgery, Monash University, Melbourne, VIC, Australia., Al-Habbal Y; Upper Gastrointestinal Surgery Unit, Western Health, Footscray, VIC, Australia., Liew CH; Upper Gastrointestinal Surgery Unit, Bendigo Health, Bendigo, VIC, Australia., Bohmer R; Upper Gastrointestinal Surgery Unit, Royal Hobart Hospital, Hobart, TAS, Australia., Daruwalla J; Upper Gastrointestinal Surgery Unit, Launceston General Hospital, Launceston, TAS, Australia., Ballal M; Upper Gastrointestinal Surgery Unit, Fiona Standley Hospital, Perth, WA, Australia., Ranjan R; Upper Gastrointestinal Surgery Unit, Christchurch Hospital, Christchurch, New Zealand., MacCormick AD; Upper Gastrointestinal Surgery Unit, Middlemore Hospital, Auckland, New Zealand.; Department of Surgery, University of Auckland, Auckland, New Zealand., Pattison S; Southern Blood and Cancer Service, Health New Zealand Te Whatu Ora-Southern, Auckland, New Zealand.; Department of Pathology, Otago Medical School-Dunedin Campus, University of Otago Ōtākou Whakaihu Waka, Dunedin, New Zealand., Evennett N; Upper Gastrointestinal Surgery Unit, Auckland City Hospital, Auckland, New Zealand., Robertson J; Upper Gastrointestinal Surgery Unit, North Shore Hospital, Auckland, New Zealand., Tan J; Upper Gastrointestinal Surgery Unit, North Shore Hospital, Auckland, New Zealand., Gordon A; Upper Gastrointestinal Surgery Unit, Palmerston North Hospital, Palmerston, New Zealand., Bann S; Upper Gastrointestinal Surgery Unit, Wellington Regional Hospital, Wellington, New Zealand., Samarasam I; Upper Gastrointestinal Surgery Unit, Christian Medical College Hospital, Vellore, India., Gurunathan R; Cengild G.I. Medical Center, Kuala Lumpur, Malaysia., So J; Division of General Surgery, Department of Surgery, National University Hospital, Singapore, Singapore.; Division of Surgical Oncology, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yeung J; Department of Surgery, Toronto General Hospital, Toronto, Canada., Ferri L; Division of Thoracic and Upper Gastrointestinal Surgery, McGill University Health Centre, Montreal, Canada., Griffiths EA; Department of Upper GI Surgery, Queen Elizabeth Hospital, Birmingham, England.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England., Phillips AW; Northern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, England., Markar SR; Surgical Interventional Trials Unit, Nuffield Department of Surgical Sciences, Oxford University Hospital, London, England., Chan D; Department of Surgery, University Hospitals Plymouth, Plymouth, England., Murphy T; Department of Surgery, Mercy University Hospital, Cork, Ireland., Reynolds J; Upper Gastrointestinal Surgery Unit, St James Hospital, Dublin, Ireland., Nilsson M; Karolinska University Hospital and CLINTEC Karolinska Institutet, Stockholm, Sweden., Piessen G; Department of Digestive and Oncological Surgery, Lille University Hospital, Lille, France., Wijnhoven B; Department of Surgery, Erasmus University Medical Center, Rotterdam, Netherlands., van Hillegersberg R; Department of Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., van Berge Henegouwen MI; Department of Surgery, Amsterdam UMC, Amsterdam, Netherlands., Lombardi PM; Surgical Oncology, Niguarda Cancer Center, Milan, Italy., Liu DS; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia.; Department of Surgery, The University of Melbourne, Parkville, Melbourne, VIC, 3000, Australia.; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia.; Department of Surgery, Victorian Interventional Research and Trials Unit, University of Melbourne, Austin Precinct, Heidelberg, VIC, Australia. |
| Corporate Authors: | SPACE-FLOT Investigators |
| Source: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2026 Jul; Vol. 29 (4), pp. 827-840. Date of Electronic Publication: 2026 Apr 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 100886238 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3305 (Electronic) Linking ISSN: 14363291 NLM ISO Abbreviation: Gastric Cancer Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42043496 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Total versus subtotal gastrectomy following neoadjuvant flot chemotherapy for distal diffuse gastric adenocarcinoma: an international cohort study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sivakumar+J%22">Sivakumar J</searchLink>; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia. sivakumar.jonathan@gmail.com.; Department of Surgery, The University of Melbourne, Parkville, Melbourne, VIC, 3000, Australia. sivakumar.jonathan@gmail.com.<br /><searchLink fieldCode="AU" term="%22Wong+DJ%22">Wong DJ</searchLink>; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hall+K%22">Hall K</searchLink>; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia.; Department of Surgery, Victorian Interventional Research and Trials Unit, University of Melbourne, Austin Precinct, Heidelberg, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+MM%22">Lee MM</searchLink>; Department of Medical Oncology, Box Hill Hospital, Box Hill, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Duong+CP%22">Duong CP</searchLink>; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Watson+DI%22">Watson DI</searchLink>; College of Medicine and Public Health, Flinders University, Flinders, South Australia, Australia.; Department of Surgery, Flinders Medical Centre, Flinders, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Donohoe+CL%22">Donohoe CL</searchLink>; Upper Gastrointestinal Surgery Unit, St James Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Bright+T%22">Bright T</searchLink>; College of Medicine and Public Health, Flinders University, Flinders, South Australia, Australia.; Department of Surgery, Flinders Medical Centre, Flinders, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Aly+A%22">Aly A</searchLink>; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+K%22">Chan K</searchLink>; Upper Gastrointestinal Surgery Unit, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+DL%22">Chan DL</searchLink>; Upper Gastrointestinal Surgery Unit, Royal Northshore Hospital, St Leonards, New South Wales, Australia.; Northern Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Merrett+N%22">Merrett N</searchLink>; Upper Gastrointestinal Surgical Unit, Bankstown-Lidcombe Hospital, Bankstown, NSW, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Gananadha+S%22">Gananadha S</searchLink>; Upper Gastrointestinal Surgery Unit, Canberra Hospital, Canberra, Australia.<br /><searchLink fieldCode="AU" term="%22Lam+YH%22">Lam YH</searchLink>; Upper Gastrointestinal Surgery Unit, Lyell McEwin Hospital, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Kanhere+H%22">Kanhere H</searchLink>; Upper Gastrointestinal Surgery Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Smithers+B%22">Smithers B</searchLink>; Upper Gastrointestinal Surgery Unit, Princess Alexandra Hospital, University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Bozin+M%22">Bozin M</searchLink>; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Read+M%22">Read M</searchLink>; Upper Gastrointestinal Surgery Unit, St Vincent's Hospital, Fitzroy, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mori+K%22">Mori K</searchLink>; Upper Gastrointestinal Surgery Unit, Northern Hospital, Epping, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Johnson+MA%22">Johnson MA</searchLink>; Upper Gastrointestinal Surgery Unit, Box Hill Hospital, Box Hill, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Wong+E%22">Wong E</searchLink>; Upper Gastrointestinal Surgery Unit, Box Hill Hospital, Box Hill, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Martin+SA%22">Martin SA</searchLink>; Upper Gastrointestinal Surgery Unit, Monash Medical Centre, Epping, VIC, Australia.; Department of Surgery, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ooi+G%22">Ooi G</searchLink>; Upper Gastrointestinal Surgery Unit, Monash Medical Centre, Epping, VIC, Australia.; Department of Surgery, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Al-Habbal+Y%22">Al-Habbal Y</searchLink>; Upper Gastrointestinal Surgery Unit, Western Health, Footscray, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Liew+CH%22">Liew CH</searchLink>; Upper Gastrointestinal Surgery Unit, Bendigo Health, Bendigo, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bohmer+R%22">Bohmer R</searchLink>; Upper Gastrointestinal Surgery Unit, Royal Hobart Hospital, Hobart, TAS, Australia.<br /><searchLink fieldCode="AU" term="%22Daruwalla+J%22">Daruwalla J</searchLink>; Upper Gastrointestinal Surgery Unit, Launceston General Hospital, Launceston, TAS, Australia.<br /><searchLink fieldCode="AU" term="%22Ballal+M%22">Ballal M</searchLink>; Upper Gastrointestinal Surgery Unit, Fiona Standley Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Ranjan+R%22">Ranjan R</searchLink>; Upper Gastrointestinal Surgery Unit, Christchurch Hospital, Christchurch, New Zealand.<br /><searchLink fieldCode="AU" term="%22MacCormick+AD%22">MacCormick AD</searchLink>; Upper Gastrointestinal Surgery Unit, Middlemore Hospital, Auckland, New Zealand.; Department of Surgery, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Pattison+S%22">Pattison S</searchLink>; Southern Blood and Cancer Service, Health New Zealand Te Whatu Ora-Southern, Auckland, New Zealand.; Department of Pathology, Otago Medical School-Dunedin Campus, University of Otago Ōtākou Whakaihu Waka, Dunedin, New Zealand.<br /><searchLink fieldCode="AU" term="%22Evennett+N%22">Evennett N</searchLink>; Upper Gastrointestinal Surgery Unit, Auckland City Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Robertson+J%22">Robertson J</searchLink>; Upper Gastrointestinal Surgery Unit, North Shore Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Tan+J%22">Tan J</searchLink>; Upper Gastrointestinal Surgery Unit, North Shore Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Gordon+A%22">Gordon A</searchLink>; Upper Gastrointestinal Surgery Unit, Palmerston North Hospital, Palmerston, New Zealand.<br /><searchLink fieldCode="AU" term="%22Bann+S%22">Bann S</searchLink>; Upper Gastrointestinal Surgery Unit, Wellington Regional Hospital, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Samarasam+I%22">Samarasam I</searchLink>; Upper Gastrointestinal Surgery Unit, Christian Medical College Hospital, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Gurunathan+R%22">Gurunathan R</searchLink>; Cengild G.I. Medical Center, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22So+J%22">So J</searchLink>; Division of General Surgery, Department of Surgery, National University Hospital, Singapore, Singapore.; Division of Surgical Oncology, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yeung+J%22">Yeung J</searchLink>; Department of Surgery, Toronto General Hospital, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Ferri+L%22">Ferri L</searchLink>; Division of Thoracic and Upper Gastrointestinal Surgery, McGill University Health Centre, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Griffiths+EA%22">Griffiths EA</searchLink>; Department of Upper GI Surgery, Queen Elizabeth Hospital, Birmingham, England.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England.<br /><searchLink fieldCode="AU" term="%22Phillips+AW%22">Phillips AW</searchLink>; Northern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, England.<br /><searchLink fieldCode="AU" term="%22Markar+SR%22">Markar SR</searchLink>; Surgical Interventional Trials Unit, Nuffield Department of Surgical Sciences, Oxford University Hospital, London, England.<br /><searchLink fieldCode="AU" term="%22Chan+D%22">Chan D</searchLink>; Department of Surgery, University Hospitals Plymouth, Plymouth, England.<br /><searchLink fieldCode="AU" term="%22Murphy+T%22">Murphy T</searchLink>; Department of Surgery, Mercy University Hospital, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Reynolds+J%22">Reynolds J</searchLink>; Upper Gastrointestinal Surgery Unit, St James Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Nilsson+M%22">Nilsson M</searchLink>; Karolinska University Hospital and CLINTEC Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Piessen+G%22">Piessen G</searchLink>; Department of Digestive and Oncological Surgery, Lille University Hospital, Lille, France.<br /><searchLink fieldCode="AU" term="%22Wijnhoven+B%22">Wijnhoven B</searchLink>; Department of Surgery, Erasmus University Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hillegersberg+R%22">van Hillegersberg R</searchLink>; Department of Surgery, University Medical Centre Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Berge+Henegouwen+MI%22">van Berge Henegouwen MI</searchLink>; Department of Surgery, Amsterdam UMC, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Lombardi+PM%22">Lombardi PM</searchLink>; Surgical Oncology, Niguarda Cancer Center, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+DS%22">Liu DS</searchLink>; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, 3052, Australia.; Department of Surgery, The University of Melbourne, Parkville, Melbourne, VIC, 3000, Australia.; Division of Surgery, Anaesthesia and Procedural Medicine, Upper Gastrointestinal Surgery Unit Austin Hospital, Heidelberg, VIC, Australia.; Department of Surgery, Victorian Interventional Research and Trials Unit, University of Melbourne, Austin Precinct, Heidelberg, VIC, Australia. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22SPACE-FLOT+Investigators%22">SPACE-FLOT Investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100886238%22">Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</searchLink> [Gastric Cancer] 2026 Jul; Vol. 29 (4), pp. 827-840. <i>Date of Electronic Publication: </i>2026 Apr 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Tokyo%22">Springer-Verlag Tokyo </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>100886238 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1436-3305 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214363291%22">14363291 </searchLink><i>NLM ISO Abbreviation: </i>Gastric Cancer <i>Subsets: </i>MEDLINE; In Process |
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