FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades.
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| Title: | FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades. |
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| Authors: | Wang HL; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan., Weng YH; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Chiu CC; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan., Chen WS; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan., Liu SY; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan., Yeh TH; Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.; Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw. |
| Source: | Neurochemical research [Neurochem Res] 2026 Apr 27; Vol. 51 (3). Date of Electronic Publication: 2026 Apr 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42043652 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+HL%22">Wang HL</searchLink>; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Weng+YH%22">Weng YH</searchLink>; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+CC%22">Chiu CC</searchLink>; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WS%22">Chen WS</searchLink>; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+SY%22">Liu SY</searchLink>; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+TH%22">Yeh TH</searchLink>; Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.; Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227613461%22">Neurochemical research</searchLink> [Neurochem Res] 2026 Apr 27; Vol. 51 (3). <i>Date of Electronic Publication: </i>2026 Apr 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%2FPlenum+Publishers%22">Kluwer Academic/Plenum Publishers </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7613461 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-6903 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203643190%22">03643190 </searchLink><i>NLM ISO Abbreviation: </i>Neurochem Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42043652 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11064-026-04761-3 Languages: – Code: eng Text: English Titles: – TitleFull: FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang HL – PersonEntity: Name: NameFull: Weng YH – PersonEntity: Name: NameFull: Chiu CC – PersonEntity: Name: NameFull: Chen WS – PersonEntity: Name: NameFull: Liu SY – PersonEntity: Name: NameFull: Yeh TH IsPartOfRelationships: – BibEntity: Dates: – D: 27 M: 04 Text: 2026 Apr 27 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1573-6903 Numbering: – Type: volume Value: 51 – Type: issue Value: 3 Titles: – TitleFull: Neurochemical research Type: main |
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