FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades.
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| Title: | FTDP-17T Mutations Promote Formation of Phosphorylated FTDP-17T TAU Oligomers That Cause Degeneration of Dopaminergic and Hippocampal Neurons via Activating ER Stress and Mitochondrial Pro-apoptotic Cascades. |
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| Authors: | Wang HL; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan., Weng YH; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Chiu CC; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan., Chen WS; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan., Liu SY; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan., Yeh TH; Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.; Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw. |
| Source: | Neurochemical research [Neurochem Res] 2026 Apr 27; Vol. 51 (3). Date of Electronic Publication: 2026 Apr 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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