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Machine learning-based prediction model for drug target identification and MASH improvement: a comprehensive analysis of biochemical and ferroptosis/autophagy biomarkers.

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Title: Machine learning-based prediction model for drug target identification and MASH improvement: a comprehensive analysis of biochemical and ferroptosis/autophagy biomarkers.
Authors: Matboli M; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. drmarwa_matboly@med.asu.edu.eg., Elanwar A; General Surgery Department, Faculty of medicine, Ain Shams University, Cairo, 11566, Egypt., Khaled R; Translational and applied Science hub, Faculty of medicine, Ain Shams University, Cairo, 11566, Egypt., Khaled A; Bioinformatics Group, Center of Informatics Sciences (CIS), school of information technology and computer sciences, Nile University, Giza, Egypt., Eltantawy EHB; Department of Histology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt., Hamam GG; Department of Histology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt., Ahmed MY; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Fouad M; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Tarek AA; Medical Physiology, faculty of medicine, Ain shams university, Cairo, Egypt., Elmasry M; Medical Physiology, faculty of medicine, Ain shams university, Cairo, Egypt., El-Shafei MM; Pathology Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt., Aboulhoda BE; Anatomy and Embryology department, Faculty of Medicine, Cairo University, Cairo, Egypt., Diab GI; Biomedical Engineering Department, Egyptian Armed Forces, Cairo, Egypt., Aboughaleb IH; Biomedical Engineering Department, Egyptian Armed Forces, Cairo, Egypt.
Source: Journal of physiology and biochemistry [J Physiol Biochem] 2026 Apr 27; Vol. 82 (1). Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Servicio de Publicaciones de la Universidad De Navarra (departamentos de fisiología y nutrición y de bioquimica) Country of Publication: Spain NLM ID: 9812509 Publication Model: Electronic Cited Medium: Internet ISSN: 1877-8755 (Electronic) Linking ISSN: 11387548 NLM ISO Abbreviation: J Physiol Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Machine learning-based prediction model for drug target identification and MASH improvement: a comprehensive analysis of biochemical and ferroptosis/autophagy biomarkers.
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  Data: <searchLink fieldCode="AU" term="%22Matboli+M%22">Matboli M</searchLink>; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. drmarwa_matboly@med.asu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elanwar+A%22">Elanwar A</searchLink>; General Surgery Department, Faculty of medicine, Ain Shams University, Cairo, 11566, Egypt.<br /><searchLink fieldCode="AU" term="%22Khaled+R%22">Khaled R</searchLink>; Translational and applied Science hub, Faculty of medicine, Ain Shams University, Cairo, 11566, Egypt.<br /><searchLink fieldCode="AU" term="%22Khaled+A%22">Khaled A</searchLink>; Bioinformatics Group, Center of Informatics Sciences (CIS), school of information technology and computer sciences, Nile University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Eltantawy+EHB%22">Eltantawy EHB</searchLink>; Department of Histology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Hamam+GG%22">Hamam GG</searchLink>; Department of Histology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+MY%22">Ahmed MY</searchLink>; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Fouad+M%22">Fouad M</searchLink>; Medical biochemistry and molecular biology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Tarek+AA%22">Tarek AA</searchLink>; Medical Physiology, faculty of medicine, Ain shams university, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Elmasry+M%22">Elmasry M</searchLink>; Medical Physiology, faculty of medicine, Ain shams university, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Shafei+MM%22">El-Shafei MM</searchLink>; Pathology Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Aboulhoda+BE%22">Aboulhoda BE</searchLink>; Anatomy and Embryology department, Faculty of Medicine, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Diab+GI%22">Diab GI</searchLink>; Biomedical Engineering Department, Egyptian Armed Forces, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Aboughaleb+IH%22">Aboughaleb IH</searchLink>; Biomedical Engineering Department, Egyptian Armed Forces, Cairo, Egypt.
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  Data: <searchLink fieldCode="JN" term="%229812509%22">Journal of physiology and biochemistry</searchLink> [J Physiol Biochem] 2026 Apr 27; Vol. 82 (1). <i>Date of Electronic Publication: </i>2026 Apr 27.
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              Text: 2026 Apr 27
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