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Effects of increasing intranuclear calcium levels via MCU inhibition on mouse and human PSC-derived cardiomyocyte differentiation and maturation.

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Title: Effects of increasing intranuclear calcium levels via MCU inhibition on mouse and human PSC-derived cardiomyocyte differentiation and maturation.
Authors: Seo HJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea., Kim JY; New Drug Development Division, K-BioCELF Inc., Suwon 16229, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea., Cho HJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea., Lee JE; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea., Bang SB; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea., Jeon M; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea., Lee HA; Center for Biomimetic Research, Korea Institute of Toxicology (KIT), 34114 Daejeon, Korea.; School of Korea Institute of Toxicology, University of Science and Technology (UST), 34113 Daejeon, Korea., Shin YJ; Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia., Yang HM; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea., Kim HS; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.
Source: Stem cells translational medicine [Stem Cells Transl Med] 2026 Apr 27; Vol. 15 (5).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print Cited Medium: Internet ISSN: 2157-6580 (Electronic) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of increasing intranuclear calcium levels via MCU inhibition on mouse and human PSC-derived cardiomyocyte differentiation and maturation.
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  Data: <searchLink fieldCode="AU" term="%22Seo+HJ%22">Seo HJ</searchLink>; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JY%22">Kim JY</searchLink>; New Drug Development Division, K-BioCELF Inc., Suwon 16229, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+HJ%22">Cho HJ</searchLink>; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Bang+SB%22">Bang SB</searchLink>; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+M%22">Jeon M</searchLink>; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HA%22">Lee HA</searchLink>; Center for Biomimetic Research, Korea Institute of Toxicology (KIT), 34114 Daejeon, Korea.; School of Korea Institute of Toxicology, University of Science and Technology (UST), 34113 Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+YJ%22">Shin YJ</searchLink>; Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia.<br /><searchLink fieldCode="AU" term="%22Yang+HM%22">Yang HM</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.; Interdisciplinary Program in Stem Cell Biology, College of Medicine, Seoul National University, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.
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  Data: <searchLink fieldCode="JN" term="%22101578022%22">Stem cells translational medicine</searchLink> [Stem Cells Transl Med] 2026 Apr 27; Vol. 15 (5).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101578022 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2157-6580 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221576564%22">21576564 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cells Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42045130
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        Value: 10.1093/stcltm/szag021
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            – D: 27
              M: 04
              Text: 2026 Apr 27
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              Y: 2026
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