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Single-cell analysis reveals crosstalk between TREM1-positive myeloid cells and cancer-associated fibroblasts in colorectal cancer progression.

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Title: Single-cell analysis reveals crosstalk between TREM1-positive myeloid cells and cancer-associated fibroblasts in colorectal cancer progression.
Authors: Wu SY; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Chen PC; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Chan RH; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Chen CH; Department of Mathematics, University of Taipei, No. 1, Aiguo West Road, Taipei City, Taiwan., Huang YH; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Huang YJ; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Chung BS; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Shen CH; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan.; Doctoral Program in Tissue Engineering and Regenerative Medicine, Biotechnology Center, National Chung Hsing University, No. 145, Xingda Road, Taichung City, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, No. 100, Shih‑Chuan 1st Road, Kaohsiung City, Taiwan., Kuo HY; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Kang JW; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Lee CT; Department of Pathology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Tsai HJ; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan., Fang YC; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan., Lin PC; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.; Department of Genomic Medicine, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan., Yeh YM; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan. i5485111@gmail.com., Chen SH; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan. Bryanchen@nhri.edu.tw.; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan. Bryanchen@nhri.edu.tw.
Source: Journal of gastroenterology [J Gastroenterol] 2026 Apr 27. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell analysis reveals crosstalk between TREM1-positive myeloid cells and cancer-associated fibroblasts in colorectal cancer progression.
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  Data: <searchLink fieldCode="AU" term="%22Wu+SY%22">Wu SY</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+PC%22">Chen PC</searchLink>; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chan+RH%22">Chan RH</searchLink>; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; Department of Mathematics, University of Taipei, No. 1, Aiguo West Road, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YH%22">Huang YH</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YJ%22">Huang YJ</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chung+BS%22">Chung BS</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+CH%22">Shen CH</searchLink>; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan.; Doctoral Program in Tissue Engineering and Regenerative Medicine, Biotechnology Center, National Chung Hsing University, No. 145, Xingda Road, Taichung City, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, No. 100, Shih‑Chuan 1st Road, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+HY%22">Kuo HY</searchLink>; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kang+JW%22">Kang JW</searchLink>; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+CT%22">Lee CT</searchLink>; Department of Pathology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HJ%22">Tsai HJ</searchLink>; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fang+YC%22">Fang YC</searchLink>; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PC%22">Lin PC</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.; Department of Genomic Medicine, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+YM%22">Yeh YM</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan. i5485111@gmail.com.<br /><searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City, Taiwan. Bryanchen@nhri.edu.tw.; National Institute of Cancer Research, National Health Research Institutes, 2F, No. 367, Sheng Li Road, Tainan City, Taiwan. Bryanchen@nhri.edu.tw.
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        Value: 10.1007/s00535-026-02430-4
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        Text: English
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      – TitleFull: Single-cell analysis reveals crosstalk between TREM1-positive myeloid cells and cancer-associated fibroblasts in colorectal cancer progression.
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              Text: 2026 Apr 27
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