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Cardiomyocyte-Specific Plakophilin-2 Loss Is Sufficient to Induce Aging and Senescence of Nonmyocytes: Relevance to Arrhythmogenic Cardiomyopathy.

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Title: Cardiomyocyte-Specific Plakophilin-2 Loss Is Sufficient to Induce Aging and Senescence of Nonmyocytes: Relevance to Arrhythmogenic Cardiomyopathy.
Authors: Bertoli G; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY., Phadke K; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY., Cospito A; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY., Rizk JA; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY., Zhang M; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY., Miliotou E; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY.; Department of Biomedical Engineering, NYU Tandon School of Engineering New York University New York NY., Cammer M; Microscopy Laboratory, Division of Advanced Research Technologies New York University Grossman School of Medicine New York NY., Deng Y; Microscopy Laboratory, Division of Advanced Research Technologies New York University Grossman School of Medicine New York NY., Mezzano V; Experimental Pathology Research Laboratory, Division of Advanced Research Technologies NYU Grossman School of Medicine New York NY., Alu M; Experimental Pathology Research Laboratory, Division of Advanced Research Technologies NYU Grossman School of Medicine New York NY., Ward G; Experimental Pathology Research Laboratory, Division of Advanced Research Technologies NYU Grossman School of Medicine New York NY., Loomis C; Experimental Pathology Research Laboratory, Division of Advanced Research Technologies NYU Grossman School of Medicine New York NY., Heguy A; The Genome Technology Center, New York University Grossman School of Medicine New York NY., Liang FX; Microscopy Laboratory, Division of Advanced Research Technologies New York University Grossman School of Medicine New York NY., Small EM; Department of Medicine, Aab Cardiovascular Research Institute University of Rochester School of Medicine and Dentistry Rochester NY., de Lázaro I; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY.; Department of Biomedical Engineering, NYU Tandon School of Engineering New York University New York NY., Delmar M; The Leon H. Charney Division of Cardiology New York University Grossman School of Medicine New York NY.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e047447. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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