Inhibition of the Microglial cGAS-STING Pathway Improves Neurological Deficits and Long-Term Hydrocephalus Symptoms in Mice with Intraventricular Hemorrhage.
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| Title: | Inhibition of the Microglial cGAS-STING Pathway Improves Neurological Deficits and Long-Term Hydrocephalus Symptoms in Mice with Intraventricular Hemorrhage. |
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| Authors: | Wang HX; Department of Spinal surgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China.; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China., Deng HJ; Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China., Zhong KH; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China., Deng ZA; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China., Gao BC; Department of Neurosurgery, The First People's Hospital of Yunnan Province (The Affiliated Hospital of Kunming University of Science and Technology) Kunming, Yunnan, Kunming, China, 650000., Tang X; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China., Li YY; Department of Pediatric Neurosurgery , West China Second University Hospital, Sichuan University, Sichuan, Chengdu, 610041, China., Huang KR; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China., Tong AP; State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, Chengdu, China, Sichuan Province, 610041. aipingtong@scu.edu.cn., Feng DX; Department of Spinal surgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China., Zhou LX; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China. zhlxlll@163.com.; Department of Neurosurgery, NHC Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), School of Medicine, University of Electronic Science and Technology of China, Sichuan Province, Mianyang, 621000, China. zhlxlll@163.com.; Department of Neurosurgery, Fifth People's Hospital of Ningxia Hui Autonomous Region, Ningxia, Shizuishan, 753000, China. zhlxlll@163.com. |
| Source: | Molecular neurobiology [Mol Neurobiol] 2026 Apr 29; Vol. 63 (1). Date of Electronic Publication: 2026 Apr 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42050115 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Inhibition of the Microglial cGAS-STING Pathway Improves Neurological Deficits and Long-Term Hydrocephalus Symptoms in Mice with Intraventricular Hemorrhage. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+HX%22">Wang HX</searchLink>; Department of Spinal surgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China.; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Deng+HJ%22">Deng HJ</searchLink>; Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China.<br /><searchLink fieldCode="AU" term="%22Zhong+KH%22">Zhong KH</searchLink>; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Deng+ZA%22">Deng ZA</searchLink>; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Gao+BC%22">Gao BC</searchLink>; Department of Neurosurgery, The First People's Hospital of Yunnan Province (The Affiliated Hospital of Kunming University of Science and Technology) Kunming, Yunnan, Kunming, China, 650000.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Li+YY%22">Li YY</searchLink>; Department of Pediatric Neurosurgery , West China Second University Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Huang+KR%22">Huang KR</searchLink>; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Tong+AP%22">Tong AP</searchLink>; State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, Chengdu, China, Sichuan Province, 610041. aipingtong@scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Feng+DX%22">Feng DX</searchLink>; Department of Spinal surgery, The Affiliated Hospital, Southwest Medical University, Sichuan Province, Luzhou, 646000, China.<br /><searchLink fieldCode="AU" term="%22Zhou+LX%22">Zhou LX</searchLink>; Department of Neurosurgery, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China. zhlxlll@163.com.; Department of Neurosurgery, NHC Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), School of Medicine, University of Electronic Science and Technology of China, Sichuan Province, Mianyang, 621000, China. zhlxlll@163.com.; Department of Neurosurgery, Fifth People's Hospital of Ningxia Hui Autonomous Region, Ningxia, Shizuishan, 753000, China. zhlxlll@163.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228900963%22">Molecular neurobiology</searchLink> [Mol Neurobiol] 2026 Apr 29; Vol. 63 (1). <i>Date of Electronic Publication: </i>2026 Apr 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Humana+Press%22">Humana Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8900963 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-1182 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208937648%22">08937648 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurobiol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42050115 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s12035-026-05888-8 Languages: – Code: eng Text: English Titles: – TitleFull: Inhibition of the Microglial cGAS-STING Pathway Improves Neurological Deficits and Long-Term Hydrocephalus Symptoms in Mice with Intraventricular Hemorrhage. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang HX – PersonEntity: Name: NameFull: Deng HJ – PersonEntity: Name: NameFull: Zhong KH – PersonEntity: Name: NameFull: Deng ZA – PersonEntity: Name: NameFull: Gao BC – PersonEntity: Name: NameFull: Tang X – PersonEntity: Name: NameFull: Li YY – PersonEntity: Name: NameFull: Huang KR – PersonEntity: Name: NameFull: Tong AP – PersonEntity: Name: NameFull: Feng DX – PersonEntity: Name: NameFull: Zhou LX IsPartOfRelationships: – BibEntity: Dates: – D: 29 M: 04 Text: 2026 Apr 29 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1559-1182 Numbering: – Type: volume Value: 63 – Type: issue Value: 1 Titles: – TitleFull: Molecular neurobiology Type: main |
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