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GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.

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Title: GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.
Authors: Müller J; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany., Sofyali E; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany., Schwarzmüller L; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany., Aylon Y; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100, Rehovot, Israel., Weizman E; G-INCPM, Weizmann Institute of Science, 76100, Rehovot, Israel., Schlicker L; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany., Kelly K; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Borgoni S; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany., Oz S; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Stocker C; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany., Burmester S; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Wörner A; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Karolus S; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Michels BE; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Heiss D; Cellular Tools Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Will R; Cellular Tools Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., de Melo Costa VR; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Lutsik P; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Weichenhan D; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Hofmann I; Antibody Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Nataraj NB; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.; Bugworks Research Inc., Center for Cellular and Molecular Platforms, National Center for Biological Sciences, TIFR GKVK Campus, Bellary Road, Bangalore, 560 065, India., Yarden Y; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, 76100, Rehovot, Israel., Magnani L; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.; Breast Epigenetic Plasticity and Evolution Group, The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP, UK., Plass C; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Schulze A; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany., Körner C; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Oren M; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100, Rehovot, Israel., Wiemann S; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany. s.wiemann@dkfz.de.
Source: Clinical epigenetics [Clin Epigenetics] 2026 Apr 29; Vol. 18 (1). Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Müller+J%22">Müller J</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sofyali+E%22">Sofyali E</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schwarzmüller+L%22">Schwarzmüller L</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Aylon+Y%22">Aylon Y</searchLink>; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Weizman+E%22">Weizman E</searchLink>; G-INCPM, Weizmann Institute of Science, 76100, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Schlicker+L%22">Schlicker L</searchLink>; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kelly+K%22">Kelly K</searchLink>; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Borgoni+S%22">Borgoni S</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Oz+S%22">Oz S</searchLink>; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Stocker+C%22">Stocker C</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Burmester+S%22">Burmester S</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wörner+A%22">Wörner A</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Karolus+S%22">Karolus S</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Michels+BE%22">Michels BE</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Heiss+D%22">Heiss D</searchLink>; Cellular Tools Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Will+R%22">Will R</searchLink>; Cellular Tools Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22de+Melo+Costa+VR%22">de Melo Costa VR</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lutsik+P%22">Lutsik P</searchLink>; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weichenhan+D%22">Weichenhan D</searchLink>; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hofmann+I%22">Hofmann I</searchLink>; Antibody Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Nataraj+NB%22">Nataraj NB</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.; Bugworks Research Inc., Center for Cellular and Molecular Platforms, National Center for Biological Sciences, TIFR GKVK Campus, Bellary Road, Bangalore, 560 065, India.<br /><searchLink fieldCode="AU" term="%22Yarden+Y%22">Yarden Y</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Magnani+L%22">Magnani L</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.; Breast Epigenetic Plasticity and Evolution Group, The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP, UK.<br /><searchLink fieldCode="AU" term="%22Plass+C%22">Plass C</searchLink>; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+A%22">Schulze A</searchLink>; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Körner+C%22">Körner C</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Oren+M%22">Oren M</searchLink>; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Wiemann+S%22">Wiemann S</searchLink>; Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany. s.wiemann@dkfz.de.
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  Data: <searchLink fieldCode="JN" term="%22101516977%22">Clinical epigenetics</searchLink> [Clin Epigenetics] 2026 Apr 29; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Apr 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101516977 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-7083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218687075%22">18687075 </searchLink><i>NLM ISO Abbreviation: </i>Clin Epigenetics <i>Subsets: </i>MEDLINE
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