Increased presynaptic dopamine activity in adolescent with major depressive disorder: an 18F-FDOPA PET study.

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Title: Increased presynaptic dopamine activity in adolescent with major depressive disorder: an 18F-FDOPA PET study.
Authors: Sun XZ; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Qingdao Mental Health Center, Qingdao, 266034, Shandong, China., Cai YX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Cai QJ; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Ling XY; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Zhang GM; The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China., Lin JJ; Department of Clinical Psychology, The Eighth Affiliated Hospital, Sun Yat-Sen University, China., Liu YX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Shi X; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wang TZ; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wu B; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Tang YJ; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Fan XX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Zhao Y; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wang L; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: l_wang1009@jnu.edu.cn., Xu H; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: txh@jnu.edu.cn., Pan JY; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: jiypan@163.com.
Source: Journal of affective disorders [J Affect Disord] 2026 Oct 01; Vol. 410, pp. 121884. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-2517
DOI:10.1016/j.jad.2026.121884