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Increased presynaptic dopamine activity in adolescent with major depressive disorder: an 18F-FDOPA PET study.

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Title: Increased presynaptic dopamine activity in adolescent with major depressive disorder: an 18F-FDOPA PET study.
Authors: Sun XZ; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Qingdao Mental Health Center, Qingdao, 266034, Shandong, China., Cai YX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Cai QJ; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Ling XY; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Zhang GM; The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China., Lin JJ; Department of Clinical Psychology, The Eighth Affiliated Hospital, Sun Yat-Sen University, China., Liu YX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Shi X; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wang TZ; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wu B; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Tang YJ; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Fan XX; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Zhao Y; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China., Wang L; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: l_wang1009@jnu.edu.cn., Xu H; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: txh@jnu.edu.cn., Pan JY; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: jiypan@163.com.
Source: Journal of affective disorders [J Affect Disord] 2026 Oct 01; Vol. 410, pp. 121884. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased presynaptic dopamine activity in adolescent with major depressive disorder: an <superscript>18</superscript>F-FDOPA PET study.
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  Data: <searchLink fieldCode="AU" term="%22Sun+XZ%22">Sun XZ</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Qingdao Mental Health Center, Qingdao, 266034, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Cai+YX%22">Cai YX</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Cai+QJ%22">Cai QJ</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Ling+XY%22">Ling XY</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Zhang+GM%22">Zhang GM</searchLink>; The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.<br /><searchLink fieldCode="AU" term="%22Lin+JJ%22">Lin JJ</searchLink>; Department of Clinical Psychology, The Eighth Affiliated Hospital, Sun Yat-Sen University, China.<br /><searchLink fieldCode="AU" term="%22Liu+YX%22">Liu YX</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Wang+TZ%22">Wang TZ</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Tang+YJ%22">Tang YJ</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Fan+XX%22">Fan XX</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: l_wang1009@jnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Nuclear Medicine, Key Laboratory of Basic and Translational Research On Radiopharmaceuticals, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: txh@jnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Pan+JY%22">Pan JY</searchLink>; Department of Sleep Medicine Centre, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Department of Psychiatry, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: jiypan@163.com.
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  Data: <searchLink fieldCode="JN" term="%227906073%22">Journal of affective disorders</searchLink> [J Affect Disord] 2026 Oct 01; Vol. 410, pp. 121884. <i>Date of Electronic Publication: </i>2026 Apr 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2FNorth-Holland+Biomedical+Press%22">Elsevier/North-Holland Biomedical Press </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7906073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2517 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201650327%22">01650327 </searchLink><i>NLM ISO Abbreviation: </i>J Affect Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jad.2026.121884
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      – Code: eng
        Text: English
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        StartPage: 121884
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      – TitleFull: Increased presynaptic dopamine activity in adolescent with major depressive disorder: an 18F-FDOPA PET study.
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              Text: 2026 Oct 01
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