Effect of statins and ACE inhibitors on the metabolome in the Adolescent Type 1 Diabetes cardio-renal Intervention Trial (AdDIT) cohort.

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Title: Effect of statins and ACE inhibitors on the metabolome in the Adolescent Type 1 Diabetes cardio-renal Intervention Trial (AdDIT) cohort.
Authors: Prampolini B; Department of Medical and Surgical Sciences for Mothers, Children and Adults - Post-Graduate School of Pediatrics, University of Modena and Reggio Emilia, Modena, Italy., Giton A; Institute of Cardiovascular Science, University College London, London, UK., Frassineti S; Institute of Cardiovascular Science, University College London, London, UK., Benitez-Aguirre P; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia., Cameron FJ; Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, VIC, Australia.; Murdoch Children's Research Institute, Melbourne, VIC, Australia.; The University of Melbourne, Melbourne, VIC, Australia., Craig ME; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia.; Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Couper JJ; Endocrinology and Diabetes Centre, Women's and Children's Hospital, Robinson Institute, University of Adelaide, Adelaide, SA, Australia., Dalton RN; Well Child Laboratory, St Thomas' Hospital, Evelina London Children's Hospital, London, UK., Daneman D; Division of Endocrinology, Hospital for Sick Children, Toronto, ON, Canada., Davis EA; Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, WA, Australia.; The Kids Research Institute Australia, Nedlands, WA, Australia., Donaghue KC; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia., Jones TW; Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, WA, Australia.; The Kids Research Institute Australia, Nedlands, WA, Australia., Mahmud FH; Division of Endocrinology, Hospital for Sick Children, Toronto, ON, Canada., Marshall SM; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK., Neil HA; Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, UK., Deanfield JE; Institute of Cardiovascular Science, University College London, London, UK., Marcovecchio ML; Department of Paediatrics, University of Cambridge, Cambridge, UK. mlm45@medschl.cam.ac.uk.; Department of Paediatric Diabetes and Endocrinology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. mlm45@medschl.cam.ac.uk., Chiesa ST; Institute of Cardiovascular Science, University College London, London, UK.
Source: Scientific reports [Sci Rep] 2026 Apr 29. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Effect of statins and ACE inhibitors on the metabolome in the Adolescent Type 1 Diabetes cardio-renal Intervention Trial (AdDIT) cohort.
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  Data: <searchLink fieldCode="AU" term="%22Prampolini+B%22">Prampolini B</searchLink>; Department of Medical and Surgical Sciences for Mothers, Children and Adults - Post-Graduate School of Pediatrics, University of Modena and Reggio Emilia, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Giton+A%22">Giton A</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Frassineti+S%22">Frassineti S</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Benitez-Aguirre+P%22">Benitez-Aguirre P</searchLink>; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cameron+FJ%22">Cameron FJ</searchLink>; Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, VIC, Australia.; Murdoch Children's Research Institute, Melbourne, VIC, Australia.; The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Craig+ME%22">Craig ME</searchLink>; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia.; Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Couper+JJ%22">Couper JJ</searchLink>; Endocrinology and Diabetes Centre, Women's and Children's Hospital, Robinson Institute, University of Adelaide, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Dalton+RN%22">Dalton RN</searchLink>; Well Child Laboratory, St Thomas' Hospital, Evelina London Children's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Daneman+D%22">Daneman D</searchLink>; Division of Endocrinology, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Davis+EA%22">Davis EA</searchLink>; Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, WA, Australia.; The Kids Research Institute Australia, Nedlands, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Donaghue+KC%22">Donaghue KC</searchLink>; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia.; Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Jones+TW%22">Jones TW</searchLink>; Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, WA, Australia.; The Kids Research Institute Australia, Nedlands, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Mahmud+FH%22">Mahmud FH</searchLink>; Division of Endocrinology, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Marshall+SM%22">Marshall SM</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Neil+HA%22">Neil HA</searchLink>; Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Deanfield+JE%22">Deanfield JE</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Marcovecchio+ML%22">Marcovecchio ML</searchLink>; Department of Paediatrics, University of Cambridge, Cambridge, UK. mlm45@medschl.cam.ac.uk.; Department of Paediatric Diabetes and Endocrinology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. mlm45@medschl.cam.ac.uk.<br /><searchLink fieldCode="AU" term="%22Chiesa+ST%22">Chiesa ST</searchLink>; Institute of Cardiovascular Science, University College London, London, UK.
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