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Circulating tumor cell-derived lines exhibit an amoeboid mode of migration.

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Title: Circulating tumor cell-derived lines exhibit an amoeboid mode of migration.
Authors: Belthier G; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France., Boekhorst VT; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Cell Biology, Radboud University Medical Centre, 6525 GA, Nijmegen, the Netherlands., Homayed Z; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France., Boubaker JV; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France., Grillet F; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France., Albaret MA; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France., Foroutan M; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Collaborative Centre for Genomic Cancer Medicine, Victorian Comprehensive Cancer Centre, Melbourne, VIC, Australia., De Sousa G; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France., Canterel-Thouennon L; Plateforme MPCC-SIRIC Montpellier Cancer, IRCM, Montpellier, France., Bourgaux JF; Service d'Hépato-Gastroentérologie, CHU Carémeau, Nîmes, France., Prudhomme M; Service de Chirurgie Digestive, CHU Carémeau, Nîmes, France., Samalin E; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France., Mazard T; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France., Lossaint G; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France., Khellaf L; Institut Régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.; Tumor Microenvironment and Resistance to Treatment Lab, INSERM U1194, Montpellier, France.; Université de Montpellier, Montpellier, France., Hollande F; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Collaborative Centre for Genomic Cancer Medicine, Victorian Comprehensive Cancer Centre, Melbourne, VIC, Australia., Mertani HC; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France.; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia., Friedl P; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Cell Biology, Radboud University Medical Centre, 6525 GA, Nijmegen, the Netherlands.; Cancer Genomics Center, 3584 CG, Utrecht, the Netherlands., Pannequin J; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France. julie.pannequin@igf.cnrs.fr.
Source: Scientific reports [Sci Rep] 2026 Apr 29; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process
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  Data: Circulating tumor cell-derived lines exhibit an amoeboid mode of migration.
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  Data: <searchLink fieldCode="AU" term="%22Belthier+G%22">Belthier G</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Boekhorst+VT%22">Boekhorst VT</searchLink>; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Cell Biology, Radboud University Medical Centre, 6525 GA, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Homayed+Z%22">Homayed Z</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Boubaker+JV%22">Boubaker JV</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Grillet+F%22">Grillet F</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Albaret+MA%22">Albaret MA</searchLink>; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Foroutan+M%22">Foroutan M</searchLink>; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Collaborative Centre for Genomic Cancer Medicine, Victorian Comprehensive Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22De+Sousa+G%22">De Sousa G</searchLink>; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Canterel-Thouennon+L%22">Canterel-Thouennon L</searchLink>; Plateforme MPCC-SIRIC Montpellier Cancer, IRCM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Bourgaux+JF%22">Bourgaux JF</searchLink>; Service d'Hépato-Gastroentérologie, CHU Carémeau, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Prudhomme+M%22">Prudhomme M</searchLink>; Service de Chirurgie Digestive, CHU Carémeau, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Samalin+E%22">Samalin E</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France.; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Mazard+T%22">Mazard T</searchLink>; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Lossaint+G%22">Lossaint G</searchLink>; Medical Oncology Department, Institut du Cancer de Montpellier (ICM), University Montpellier, 34298, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Khellaf+L%22">Khellaf L</searchLink>; Institut Régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.; Tumor Microenvironment and Resistance to Treatment Lab, INSERM U1194, Montpellier, France.; Université de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Hollande+F%22">Hollande F</searchLink>; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Collaborative Centre for Genomic Cancer Medicine, Victorian Comprehensive Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mertani+HC%22">Mertani HC</searchLink>; Inserm U1052, UMR5286 Centre de Recherche en Cancérologie de Lyon, CNRS, 69000, Lyon, France.; Centre Léon Bérard, 69008, Lyon, France.; Université de Lyon 1, 69000, Lyon, France.; Plasticity, Heterogeneity and Tumour Microenvironment, International Research Laboratory - PHANTOM - CNRS and The University of Melbourne, Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Friedl+P%22">Friedl P</searchLink>; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Cell Biology, Radboud University Medical Centre, 6525 GA, Nijmegen, the Netherlands.; Cancer Genomics Center, 3584 CG, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pannequin+J%22">Pannequin J</searchLink>; Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, Montpellier, France. julie.pannequin@igf.cnrs.fr.
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