Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer.
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| Title: | Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. |
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| Authors: | Spellecy O; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Qadir J; Sunnybrook Research Institute, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Han R; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Oncology, the Fourth Affiliated Hospital, Nanjing Medical University, Nanjing, China., Zhu K; College of Food Science and Technology, Shanghai Ocean University, Shanghai, China., Xu B; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Zhang Y; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Respiratory Medicine, First Affiliated Hospital of Soochow University, Suzhou, China., Aryal I; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Lin RL; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Lin AH; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Faisal ASM; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Napier D; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Piecoro D; Department of Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Scott T; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Lin P; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Chen L; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Brewer LD; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Wang C; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA., Kyprianou N; Tisch Cancer Institute, Icahn School of Medicine, The Mount Sinai Hospital, New York, NY, USA., Guo Z; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Guo R; College of Food Science and Technology, Shanghai Ocean University, Shanghai, China. rhguo@shou.edu.cn., Thibault O; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA. othibau@uky.edu., Yang BB; Sunnybrook Research Institute, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. byang@sri.utoronto.ca., Yang XH; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA. xya222@uky.edu. |
| Source: | Oncogene [Oncogene] 2026 Jul; Vol. 45 (24), pp. 2327-2341. Date of Electronic Publication: 2026 Apr 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42056559 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Spellecy+O%22">Spellecy O</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Qadir+J%22">Qadir J</searchLink>; Sunnybrook Research Institute, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Han+R%22">Han R</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Oncology, the Fourth Affiliated Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+K%22">Zhu K</searchLink>; College of Food Science and Technology, Shanghai Ocean University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+B%22">Xu B</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Respiratory Medicine, First Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Aryal+I%22">Aryal I</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+RL%22">Lin RL</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+AH%22">Lin AH</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Faisal+ASM%22">Faisal ASM</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Napier+D%22">Napier D</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Piecoro+D%22">Piecoro D</searchLink>; Department of Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Scott+T%22">Scott T</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+P%22">Lin P</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Brewer+LD%22">Brewer LD</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Markey Cancer Center and Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Kyprianou+N%22">Kyprianou N</searchLink>; Tisch Cancer Institute, Icahn School of Medicine, The Mount Sinai Hospital, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Guo+R%22">Guo R</searchLink>; College of Food Science and Technology, Shanghai Ocean University, Shanghai, China. rhguo@shou.edu.cn.<br /><searchLink fieldCode="AU" term="%22Thibault+O%22">Thibault O</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA. othibau@uky.edu.<br /><searchLink fieldCode="AU" term="%22Yang+BB%22">Yang BB</searchLink>; Sunnybrook Research Institute, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. byang@sri.utoronto.ca.<br /><searchLink fieldCode="AU" term="%22Yang+XH%22">Yang XH</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA. xya222@uky.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Jul; Vol. 45 (24), pp. 2327-2341. <i>Date of Electronic Publication: </i>2026 Apr 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42056559 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41388-026-03780-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2327 Titles: – TitleFull: Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Spellecy O – PersonEntity: Name: NameFull: Qadir J – PersonEntity: Name: NameFull: Han R – PersonEntity: Name: NameFull: Zhu K – PersonEntity: Name: NameFull: Xu B – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Aryal I – PersonEntity: Name: NameFull: Lin RL – PersonEntity: Name: NameFull: Lin AH – PersonEntity: Name: NameFull: Faisal ASM – PersonEntity: Name: NameFull: Napier D – PersonEntity: Name: NameFull: Piecoro D – PersonEntity: Name: NameFull: Scott T – PersonEntity: Name: NameFull: Lin P – PersonEntity: Name: NameFull: Chen L – PersonEntity: Name: NameFull: Brewer LD – PersonEntity: Name: NameFull: Wang C – PersonEntity: Name: NameFull: Kyprianou N – PersonEntity: Name: NameFull: Guo Z – PersonEntity: Name: NameFull: Guo R – PersonEntity: Name: NameFull: Thibault O – PersonEntity: Name: NameFull: Yang BB – PersonEntity: Name: NameFull: Yang XH IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5594 Numbering: – Type: volume Value: 45 – Type: issue Value: 24 Titles: – TitleFull: Oncogene Type: main |
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