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Synergistic effect of IL-4 and simulated microgravity on osteogenic differentiation of periosteal stem cells.

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Title: Synergistic effect of IL-4 and simulated microgravity on osteogenic differentiation of periosteal stem cells.
Authors: Liu LJ; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China; Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Lu FX; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China., Yang X; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China., Fan YB; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China., Wu ZH; Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China., Wu XT; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. Electronic address: xintongw@buaa.edu.cn., Sun LW; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. Electronic address: sunlw@buaa.edu.cn.
Source: Life sciences in space research [Life Sci Space Res (Amst)] 2026 May; Vol. 50, pp. 106-112. Date of Electronic Publication: 2026 Jan 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101632373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2214-5532 (Electronic) Linking ISSN: 22145524 NLM ISO Abbreviation: Life Sci Space Res (Amst) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synergistic effect of IL-4 and simulated microgravity on osteogenic differentiation of periosteal stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Liu+LJ%22">Liu LJ</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China; Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.<br /><searchLink fieldCode="AU" term="%22Lu+FX%22">Lu FX</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.<br /><searchLink fieldCode="AU" term="%22Fan+YB%22">Fan YB</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.<br /><searchLink fieldCode="AU" term="%22Wu+ZH%22">Wu ZH</searchLink>; Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.<br /><searchLink fieldCode="AU" term="%22Wu+XT%22">Wu XT</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. Electronic address: xintongw@buaa.edu.cn.<br /><searchLink fieldCode="AU" term="%22Sun+LW%22">Sun LW</searchLink>; Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. Electronic address: sunlw@buaa.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101632373%22">Life sciences in space research</searchLink> [Life Sci Space Res (Amst)] 2026 May; Vol. 50, pp. 106-112. <i>Date of Electronic Publication: </i>2026 Jan 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101632373 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2214-5532 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222145524%22">22145524 </searchLink><i>NLM ISO Abbreviation: </i>Life Sci Space Res (Amst) <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.lssr.2026.01.004
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      – Code: eng
        Text: English
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        StartPage: 106
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      – TitleFull: Synergistic effect of IL-4 and simulated microgravity on osteogenic differentiation of periosteal stem cells.
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            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
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              Value: 2214-5532
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              Value: 50
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