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Aging-Related Morphological Change in Regional Lymph Nodes Promote an Immunosuppressive Microenvironment in Colorectal Cancer.

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Title: Aging-Related Morphological Change in Regional Lymph Nodes Promote an Immunosuppressive Microenvironment in Colorectal Cancer.
Authors: Kanemitsu K; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Yamada R; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Yoshii D; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Fujiwara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Tagayasu Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Sako T; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Arima K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Yamashita K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Harada K; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Hanada N; Department of Surgery, Izumi General Medical Center, Kagoshima, Japan., Iwatsuki M; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
Source: Acta histochemica et cytochemica [Acta Histochem Cytochem] 2026 Apr 25; Vol. 59 (2), pp. 69-74. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Nippon Soshiki Saibo Kagakukai Country of Publication: Japan NLM ID: 0147110 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0044-5991 (Print) Linking ISSN: 00445991 NLM ISO Abbreviation: Acta Histochem Cytochem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Aging-Related Morphological Change in Regional Lymph Nodes Promote an Immunosuppressive Microenvironment in Colorectal Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Kanemitsu+K%22">Kanemitsu K</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+R%22">Yamada R</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshii+D%22">Yoshii D</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Fujiwara+Y%22">Fujiwara Y</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Tagayasu+Y%22">Tagayasu Y</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Sako+T%22">Sako T</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Arima+K%22">Arima K</searchLink>; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yamashita+K%22">Yamashita K</searchLink>; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Harada+K%22">Harada K</searchLink>; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Hanada+N%22">Hanada N</searchLink>; Department of Surgery, Izumi General Medical Center, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Iwatsuki+M%22">Iwatsuki M</searchLink>; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Komohara+Y%22">Komohara Y</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
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  Data: <searchLink fieldCode="JN" term="%220147110%22">Acta histochemica et cytochemica</searchLink> [Acta Histochem Cytochem] 2026 Apr 25; Vol. 59 (2), pp. 69-74. <i>Date of Electronic Publication: </i>2026 Apr 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nippon+Soshiki+Saibo+Kagakukai%22">Nippon Soshiki Saibo Kagakukai </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>0147110 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>0044-5991 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200445991%22">00445991 </searchLink><i>NLM ISO Abbreviation: </i>Acta Histochem Cytochem <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Apr 25
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