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Lymphoid tissue chemokines limit priming duration to preserve CD8+ T cell functionality.

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Title: Lymphoid tissue chemokines limit priming duration to preserve CD8+ T cell functionality.
Authors: Altenburger LM; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Carvoeiro DC; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Dehio P; Department of Biomedicine, University of Basel, Basel, Switzerland., Zhou J; Department of Biology, University of Fribourg, Fribourg, Switzerland., Laura C; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bofi I Cuadros À; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Katoch M; Institute of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Krüger C; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., de Albuquerque JB; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Pfenninger P; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Magdaleno JM; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Mehling M; Department of Biomedicine, University of Basel, Basel, Switzerland., Iannacone M; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Gheinani AH; Functional Urology Research Group, Department for BioMedical Research DBMR, University of Bern, Bern, Switzerland.; Department of Urology, Inselspital University Hospital, Bern, Switzerland.; Urological Diseases Research Center, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Department of Surgery, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Dengjel J; Department of Biology, University of Fribourg, Fribourg, Switzerland., Abe J; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland., Stein JV; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Source: Science (New York, N.Y.) [Science] 2026 Apr 30; Vol. 392 (6797), pp. eadq2080. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lymphoid tissue chemokines limit priming duration to preserve CD8<superscript>+</superscript> T cell functionality.
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  Data: <searchLink fieldCode="AU" term="%22Altenburger+LM%22">Altenburger LM</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Carvoeiro+DC%22">Carvoeiro DC</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dehio+P%22">Dehio P</searchLink>; Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Department of Biology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Laura+C%22">Laura C</searchLink>; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bofi+I+Cuadros+À%22">Bofi I Cuadros À</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Katoch+M%22">Katoch M</searchLink>; Institute of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Krüger+C%22">Krüger C</searchLink>; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22de+Albuquerque+JB%22">de Albuquerque JB</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pfenninger+P%22">Pfenninger P</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Magdaleno+JM%22">Magdaleno JM</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mehling+M%22">Mehling M</searchLink>; Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Iannacone+M%22">Iannacone M</searchLink>; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gheinani+AH%22">Gheinani AH</searchLink>; Functional Urology Research Group, Department for BioMedical Research DBMR, University of Bern, Bern, Switzerland.; Department of Urology, Inselspital University Hospital, Bern, Switzerland.; Urological Diseases Research Center, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Department of Surgery, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dengjel+J%22">Dengjel J</searchLink>; Department of Biology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Abe+J%22">Abe J</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stein+JV%22">Stein JV</searchLink>; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2026 Apr 30; Vol. 392 (6797), pp. eadq2080. <i>Date of Electronic Publication: </i>2026 Apr 30.
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