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Structural characterization and molecular interaction studies of a novel RNA aptamer-MC1R macromolecular system using integrated computational and experimental approaches.

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Title: Structural characterization and molecular interaction studies of a novel RNA aptamer-MC1R macromolecular system using integrated computational and experimental approaches.
Authors: Nail HM; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan., Soliman AG; Department of Biological Functions Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, 808-0196, Japan; Department of Genetics, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt., Vieira IHP; Laboratório de Bioinformática e Química Medicinal (LABIOQUIM), Fundação Oswaldo Cruz Rondônia, Porto Velho, RO, Brazil., Metwally K; Department of Biological Functions Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, 808-0196, Japan; Department of Genetics, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt., Wang HD; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung City, 404, Taiwan; Center of Applied Nanomedicine, National Cheng Kung University, Tainan, 701, Taiwan. Electronic address: davidw@dragon.nchu.edu.tw.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jun; Vol. 366, pp. 152256. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural characterization and molecular interaction studies of a novel RNA aptamer-MC1R macromolecular system using integrated computational and experimental approaches.
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  Data: <searchLink fieldCode="AU" term="%22Nail+HM%22">Nail HM</searchLink>; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Soliman+AG%22">Soliman AG</searchLink>; Department of Biological Functions Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, 808-0196, Japan; Department of Genetics, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.<br /><searchLink fieldCode="AU" term="%22Vieira+IHP%22">Vieira IHP</searchLink>; Laboratório de Bioinformática e Química Medicinal (LABIOQUIM), Fundação Oswaldo Cruz Rondônia, Porto Velho, RO, Brazil.<br /><searchLink fieldCode="AU" term="%22Metwally+K%22">Metwally K</searchLink>; Department of Biological Functions Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, 808-0196, Japan; Department of Genetics, Faculty of Agriculture, Ain Shams University, Cairo, 11241, Egypt.<br /><searchLink fieldCode="AU" term="%22Wang+HD%22">Wang HD</searchLink>; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung City, 404, Taiwan; Center of Applied Nanomedicine, National Cheng Kung University, Tainan, 701, Taiwan. Electronic address: davidw@dragon.nchu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%227909578%22">International journal of biological macromolecules</searchLink> [Int J Biol Macromol] 2026 Jun; Vol. 366, pp. 152256. <i>Date of Electronic Publication: </i>2026 Apr 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7909578 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201418130%22">01418130 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Macromol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ijbiomac.2026.152256
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      – Code: eng
        Text: English
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        StartPage: 152256
    Titles:
      – TitleFull: Structural characterization and molecular interaction studies of a novel RNA aptamer-MC1R macromolecular system using integrated computational and experimental approaches.
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            NameFull: Nail HM
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            NameFull: Soliman AG
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            NameFull: Vieira IHP
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            NameFull: Metwally K
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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              Value: 1879-0003
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            – Type: volume
              Value: 366
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            – TitleFull: International journal of biological macromolecules
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