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Development of combined mutagenesis strategy for enhanced eicosapentaenoic acid production in Schizochytrium sp.

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Title: Development of combined mutagenesis strategy for enhanced eicosapentaenoic acid production in Schizochytrium sp.
Authors: Liu KX; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Chen Q; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Chen ZL; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Jiang CY; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Wu Y; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Li XJ; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Liu XL; School of Life and Health, Nanjing Polytechnic Institute, 625 Geguan Road, Nanjing 210048, Jiangsu, China., Cao MJ; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Ren B; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Yang YQ; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China., Guo DS; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China. Electronic address: guodongs@njnu.edu.cn.
Source: Bioresource technology [Bioresour Technol] 2026 Aug; Vol. 454, pp. 134743. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of combined mutagenesis strategy for enhanced eicosapentaenoic acid production in Schizochytrium sp.
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  Data: <searchLink fieldCode="AU" term="%22Liu+KX%22">Liu KX</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Chen+ZL%22">Chen ZL</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Jiang+CY%22">Jiang CY</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Li+XJ%22">Li XJ</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Liu+XL%22">Liu XL</searchLink>; School of Life and Health, Nanjing Polytechnic Institute, 625 Geguan Road, Nanjing 210048, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Cao+MJ%22">Cao MJ</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Ren+B%22">Ren B</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Yang+YQ%22">Yang YQ</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Guo+DS%22">Guo DS</searchLink>; State Key Laboratory of Microbial Technology, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210023, Jiangsu, China. Electronic address: guodongs@njnu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229889523%22">Bioresource technology</searchLink> [Bioresour Technol] 2026 Aug; Vol. 454, pp. 134743. <i>Date of Electronic Publication: </i>2026 Apr 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Applied+Science%22">Elsevier Applied Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9889523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2976 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608524%22">09608524 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Technol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.biortech.2026.134743
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      – Code: eng
        Text: English
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        StartPage: 134743
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      – TitleFull: Development of combined mutagenesis strategy for enhanced eicosapentaenoic acid production in Schizochytrium sp.
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              M: 08
              Text: 2026 Aug
              Type: published
              Y: 2026
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