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Oncogenic DCTPP1/MYC feedback loop rewires pyrimidine metabolism to drive hepatocellular carcinoma.

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Title: Oncogenic DCTPP1/MYC feedback loop rewires pyrimidine metabolism to drive hepatocellular carcinoma.
Authors: Li J; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China., Liang J; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China., Zhang M; Gansu Provincial Hospital, Lanzhou, China., Ma R; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; The First Affiliated Hospital of Xi'an Jiao tong University, Xi'an, China., Zhou R; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; The First Affiliated Hospital of Xi'an Jiao tong University, Xi'an, China., Xi J; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China., Yu H; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China., Li Y; Gansu Provincial Hospital, Lanzhou, China., Wang C; Institute of Pathology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China., Bai Z; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China. ldyy_baizht@lzu.edu.cn.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China. ldyy_baizht@lzu.edu.cn.
Source: Functional & integrative genomics [Funct Integr Genomics] 2026 May 01; Vol. 26 (1). Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oncogenic DCTPP1/MYC feedback loop rewires pyrimidine metabolism to drive hepatocellular carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.<br /><searchLink fieldCode="AU" term="%22Liang+J%22">Liang J</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Gansu Provincial Hospital, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Ma+R%22">Ma R</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; The First Affiliated Hospital of Xi'an Jiao tong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhou+R%22">Zhou R</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; The First Affiliated Hospital of Xi'an Jiao tong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Xi+J%22">Xi J</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Gansu Provincial Hospital, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Institute of Pathology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Bai+Z%22">Bai Z</searchLink>; Key Laboratory of Biotherapy and Regenerative Medicine, The First School of Clinical Medicine, Lanzhou University, No. 1, Donggang West Road, Lanzhou, 730000, Gansu Province, China. ldyy_baizht@lzu.edu.cn.; Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu Province, China. ldyy_baizht@lzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100939343%22">Functional & integrative genomics</searchLink> [Funct Integr Genomics] 2026 May 01; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 May 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100939343 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-7948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221438793X%22">1438793X </searchLink><i>NLM ISO Abbreviation: </i>Funct Integr Genomics <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10142-026-01870-8
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            – D: 01
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              Text: 2026 May 01
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