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Chronic lymphocytic leukemia with IGH::BCL3-translocation is characterized by a homogeneous and distinct genetic and epigenetic landscape.

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Title: Chronic lymphocytic leukemia with IGH::BCL3-translocation is characterized by a homogeneous and distinct genetic and epigenetic landscape.
Authors: Drewes C; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., López C; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; Molecular Pathology of Lymphoid Neoplasms Group Institut d'Investigaciones Biomèdiques August Pi i Sunyer (IDIBAPS) Barcelona Spain.; Hematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.; Departament de Fonaments Clínics Universitat de Barcelona Barcelona Spain., Martinez-Manjón JE; Department of Computer Science and Artificial Intelligence University of Granada, Andalusian Research Institute in Data Science and Computational Intelligence Granada Spain.; Instituto de Investigación Sanitaria ibs, GRANADA, Hospitales Universitarios de Granada-Universidad de Granada Granada Spain., Okeke N; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Jebaraj B; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany., Bens S; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Brändl B; Department of Psychiatry and Psychotherapy Zentrum für Integrative Psychiatrie gGmbH, Universitätsklinikum Schleswig-Holstein, Campus Kiel Kiel Germany., Dyer MJS; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre University of Leicester Leicester UK., Eichhorst B; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany., Fischer A; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Fischer K; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany., Robrecht S; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany., Hallek M; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany., Glaser S; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Hillebrecht S; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Jayne S; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre University of Leicester Leicester UK., Kretzmer H; Department of Genome Regulation Max Planck Institute for Molecular Genetics Berlin Germany.; Digital Health Cluster, Hasso Plattner Institute for Digital Engineering, Digital Engineering Faculty University of Potsdam Potsdam Germany., Mottok A; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany., Müller FJ; Department of Psychiatry and Psychotherapy Zentrum für Integrative Psychiatrie gGmbH, Universitätsklinikum Schleswig-Holstein, Campus Kiel Kiel Germany., Schneider C; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany., Ammerpohl O; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Ulm Ulm Germany., Del Val C; Department of Computer Science and Artificial Intelligence University of Granada, Andalusian Research Institute in Data Science and Computational Intelligence Granada Spain.; Instituto de Investigación Sanitaria ibs, GRANADA, Hospitales Universitarios de Granada-Universidad de Granada Granada Spain., Stilgenbauer S; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany., Tausch E; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany., Siebert R; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Ulm Ulm Germany.
Source: HemaSphere [Hemasphere] 2026 Apr 29; Vol. 10 (5), pp. e70354. Date of Electronic Publication: 2026 Apr 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Chronic lymphocytic leukemia with IGH::BCL3-translocation is characterized by a homogeneous and distinct genetic and epigenetic landscape.
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  Data: <searchLink fieldCode="AU" term="%22Drewes+C%22">Drewes C</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22López+C%22">López C</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; Molecular Pathology of Lymphoid Neoplasms Group Institut d'Investigaciones Biomèdiques August Pi i Sunyer (IDIBAPS) Barcelona Spain.; Hematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.; Departament de Fonaments Clínics Universitat de Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Manjón+JE%22">Martinez-Manjón JE</searchLink>; Department of Computer Science and Artificial Intelligence University of Granada, Andalusian Research Institute in Data Science and Computational Intelligence Granada Spain.; Instituto de Investigación Sanitaria ibs, GRANADA, Hospitales Universitarios de Granada-Universidad de Granada Granada Spain.<br /><searchLink fieldCode="AU" term="%22Okeke+N%22">Okeke N</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Jebaraj+B%22">Jebaraj B</searchLink>; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Bens+S%22">Bens S</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Brändl+B%22">Brändl B</searchLink>; Department of Psychiatry and Psychotherapy Zentrum für Integrative Psychiatrie gGmbH, Universitätsklinikum Schleswig-Holstein, Campus Kiel Kiel Germany.<br /><searchLink fieldCode="AU" term="%22Dyer+MJS%22">Dyer MJS</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre University of Leicester Leicester UK.<br /><searchLink fieldCode="AU" term="%22Eichhorst+B%22">Eichhorst B</searchLink>; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+A%22">Fischer A</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+K%22">Fischer K</searchLink>; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany.<br /><searchLink fieldCode="AU" term="%22Robrecht+S%22">Robrecht S</searchLink>; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany.<br /><searchLink fieldCode="AU" term="%22Hallek+M%22">Hallek M</searchLink>; Department I of Internal Medicine and German CLL Study Group Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany.<br /><searchLink fieldCode="AU" term="%22Glaser+S%22">Glaser S</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Hillebrecht+S%22">Hillebrecht S</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Jayne+S%22">Jayne S</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre University of Leicester Leicester UK.<br /><searchLink fieldCode="AU" term="%22Kretzmer+H%22">Kretzmer H</searchLink>; Department of Genome Regulation Max Planck Institute for Molecular Genetics Berlin Germany.; Digital Health Cluster, Hasso Plattner Institute for Digital Engineering, Digital Engineering Faculty University of Potsdam Potsdam Germany.<br /><searchLink fieldCode="AU" term="%22Mottok+A%22">Mottok A</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Müller+FJ%22">Müller FJ</searchLink>; Department of Psychiatry and Psychotherapy Zentrum für Integrative Psychiatrie gGmbH, Universitätsklinikum Schleswig-Holstein, Campus Kiel Kiel Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+C%22">Schneider C</searchLink>; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Ammerpohl+O%22">Ammerpohl O</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Ulm Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Del+Val+C%22">Del Val C</searchLink>; Department of Computer Science and Artificial Intelligence University of Granada, Andalusian Research Institute in Data Science and Computational Intelligence Granada Spain.; Instituto de Investigación Sanitaria ibs, GRANADA, Hospitales Universitarios de Granada-Universidad de Granada Granada Spain.<br /><searchLink fieldCode="AU" term="%22Stilgenbauer+S%22">Stilgenbauer S</searchLink>; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Tausch+E%22">Tausch E</searchLink>; Division of CLL, Department of Internal Medicine III Ulm University Medical Center Ulm Germany.<br /><searchLink fieldCode="AU" term="%22Siebert+R%22">Siebert R</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center Ulm Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Ulm Ulm Germany.
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  Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2026 Apr 29; Vol. 10 (5), pp. e70354. <i>Date of Electronic Publication: </i>2026 Apr 29 (<i>Print Publication: </i>2026).
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