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Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder, highly connected ("hub"), and leader beta-cells.

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Title: Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder, highly connected ("hub"), and leader beta-cells.
Authors: Delgadillo-Silva LF; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada., Ostinelli G; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada., Provencher-Girard A; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada., Salazar S; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada., Melhem R; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada., Rutter GA; Cardiometabolic Axis, University of Montreal Hospital Research Centre (CR-CHUM) and Department of Medicine, University of Montreal, Montreal, QC, Canada.; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Lee Kong Chian School of Medicine, Nanyang Technological College, Singapore, Singapore.; Research Institute of the McGill University Health Centre, Westmount, QC, Canada.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Apr 15; Vol. 17, pp. 1802510. Date of Electronic Publication: 2026 Apr 15 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder, highly connected ("hub"), and leader beta-cells.
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              Text: 2026 Apr 15
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