The Real-World Endocrine Toxicity Profile of ICIs, VEGFR-TKIs, and Their Combination: Analysis of the FDA Adverse Event Reporting System (FAERS) Database.

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Title: The Real-World Endocrine Toxicity Profile of ICIs, VEGFR-TKIs, and Their Combination: Analysis of the FDA Adverse Event Reporting System (FAERS) Database.
Authors: Marrano N; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy., Caporusso M; Endocrinology Unit, Regional General Hospital 'Francesco Miulli', Acquaviva delle Fonti, Bari, Italy., Matino C; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy., Caruso I; Endocrinology Unit, University Hospital 'Consorziale Policlinico' of Bari, Bari, Italy., Ganini C; Division of Medical Oncology, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy., Rizzo M; Division of Medical Oncology, University Hospital 'Consorziale Policlinico' of Bari, Bari, Italy., Di Gioia L; Endocrinology Unit, Regional General Hospital 'Francesco Miulli', Acquaviva delle Fonti, Bari, Italy., Cignarelli A; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy., Perrini S; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.; Section of Endocrinology, Department of Medicine and Surgery, LUM University, Casamassima, Bari, Italy., Laviola L; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy., Porta C; Division of Medical Oncology, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy., Giorgino F; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy., Natalicchio A; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.
Source: Oncology research [Oncol Res] 2026 Apr 22; Vol. 34 (5), pp. 19. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Tech Science Press Country of Publication: United States NLM ID: 9208097 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-3906 (Electronic) Linking ISSN: 09650407 NLM ISO Abbreviation: Oncol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Marrano+N%22">Marrano N</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Caporusso+M%22">Caporusso M</searchLink>; Endocrinology Unit, Regional General Hospital 'Francesco Miulli', Acquaviva delle Fonti, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Matino+C%22">Matino C</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Caruso+I%22">Caruso I</searchLink>; Endocrinology Unit, University Hospital 'Consorziale Policlinico' of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Ganini+C%22">Ganini C</searchLink>; Division of Medical Oncology, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzo+M%22">Rizzo M</searchLink>; Division of Medical Oncology, University Hospital 'Consorziale Policlinico' of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Gioia+L%22">Di Gioia L</searchLink>; Endocrinology Unit, Regional General Hospital 'Francesco Miulli', Acquaviva delle Fonti, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Cignarelli+A%22">Cignarelli A</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Perrini+S%22">Perrini S</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.; Section of Endocrinology, Department of Medicine and Surgery, LUM University, Casamassima, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Laviola+L%22">Laviola L</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Porta+C%22">Porta C</searchLink>; Division of Medical Oncology, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Giorgino+F%22">Giorgino F</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Natalicchio+A%22">Natalicchio A</searchLink>; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.
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