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Regulatory impact of G-quadruplexes in the human carboxylesterase 2 gene on drug and lipid metabolism.

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Title: Regulatory impact of G-quadruplexes in the human carboxylesterase 2 gene on drug and lipid metabolism.
Authors: Kuroda S; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan., Nakashima S; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan., Takemoto S; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan., Nakano M; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan., Higuchi Y; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan., Uehara S; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan., Yoneda N; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan., Suemizu H; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan., Nakajima M; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan; WPI Nano Life Science Institute (WPI-NanoLSI), Kakuma-machi, Kanazawa, 920-1192, Japan., Fukami T; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan; WPI Nano Life Science Institute (WPI-NanoLSI), Kakuma-machi, Kanazawa, 920-1192, Japan. Electronic address: tatsuki@p.kanazawa-u.ac.jp.
Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2026 Jun; Vol. 68, pp. 101531. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Regulatory impact of G-quadruplexes in the human carboxylesterase 2 gene on drug and lipid metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Kuroda+S%22">Kuroda S</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.<br /><searchLink fieldCode="AU" term="%22Nakashima+S%22">Nakashima S</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.<br /><searchLink fieldCode="AU" term="%22Takemoto+S%22">Takemoto S</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.<br /><searchLink fieldCode="AU" term="%22Nakano+M%22">Nakano M</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.<br /><searchLink fieldCode="AU" term="%22Higuchi+Y%22">Higuchi Y</searchLink>; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan.<br /><searchLink fieldCode="AU" term="%22Uehara+S%22">Uehara S</searchLink>; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan.<br /><searchLink fieldCode="AU" term="%22Yoneda+N%22">Yoneda N</searchLink>; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan.<br /><searchLink fieldCode="AU" term="%22Suemizu+H%22">Suemizu H</searchLink>; Liver Engineering Laboratory, Department of Research for Humanized Model, Central Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, 210-0821, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+M%22">Nakajima M</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan; WPI Nano Life Science Institute (WPI-NanoLSI), Kakuma-machi, Kanazawa, 920-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Fukami+T%22">Fukami T</searchLink>; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan; WPI Nano Life Science Institute (WPI-NanoLSI), Kakuma-machi, Kanazawa, 920-1192, Japan. Electronic address: tatsuki@p.kanazawa-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101164773%22">Drug metabolism and pharmacokinetics</searchLink> [Drug Metab Pharmacokinet] 2026 Jun; Vol. 68, pp. 101531. <i>Date of Electronic Publication: </i>2026 Mar 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101164773 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-0920 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213474367%22">13474367 </searchLink><i>NLM ISO Abbreviation: </i>Drug Metab Pharmacokinet <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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