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Spatially resolved ex vivo drug response profiling in SMARCB1-deficient sinonasal carcinoma.

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Title: Spatially resolved ex vivo drug response profiling in SMARCB1-deficient sinonasal carcinoma.
Authors: Jurmeister P; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany. philipp.jurmeister@med.uni-muenchen.de.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany. philipp.jurmeister@med.uni-muenchen.de., Flach S; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität (LMU) Munich University Hospital, Munich, Germany., Bergmayr L; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Schleich K; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Chimal Calderon E; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., H Mochmann L; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Zhdanovich Y; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Klingler D; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Pusztai A; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Kübler A; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Walz C; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany., Westphalen CB; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), LMU University Hospital, Munich, Germany., Beck A; Center for Neuropathology, Ludwig-Maximilian-University, Munich, Germany., Leitheiser M; Institute of Pathology, Charité - Universitätsmedizin Berlin (Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health), Berlin, Germany., Breimer GE; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Rijken JA; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Devriese L; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Baumeister P; Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität (LMU) Munich University Hospital, Munich, Germany.; Bavarian Center for Cancer Research (BZKF), Munich Partner Site, Munich, Germany., Skálová A; Department of Pathology, Charles University, Faculty of Medicine in Plzen, Plzen, Czech Republic.; Bioptic Laboratory, Ltd, Plzen, Czech Republic., Schallenberg S; Institute of Pathology, Charité - Universitätsmedizin Berlin (Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health), Berlin, Germany., Klauschen F; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Center for Neuropathology, Ludwig-Maximilian-University, Munich, Germany.; Bavarian Center for Cancer Research (BZKF), Munich Partner Site, Munich, Germany.; BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany., Mock A; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Division of Translational Medical Oncology, DKFZ & National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2360-2378. Date of Electronic Publication: 2026 May 02.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: Spatially resolved ex vivo drug response profiling in SMARCB1-deficient sinonasal carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Jurmeister+P%22">Jurmeister P</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany. philipp.jurmeister@med.uni-muenchen.de.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany. philipp.jurmeister@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Flach+S%22">Flach S</searchLink>; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität (LMU) Munich University Hospital, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bergmayr+L%22">Bergmayr L</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schleich+K%22">Schleich K</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Chimal+Calderon+E%22">Chimal Calderon E</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22H+Mochmann+L%22">H Mochmann L</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zhdanovich+Y%22">Zhdanovich Y</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Klingler+D%22">Klingler D</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Pusztai+A%22">Pusztai A</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kübler+A%22">Kübler A</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Walz+C%22">Walz C</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Westphalen+CB%22">Westphalen CB</searchLink>; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), LMU University Hospital, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Beck+A%22">Beck A</searchLink>; Center for Neuropathology, Ludwig-Maximilian-University, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Leitheiser+M%22">Leitheiser M</searchLink>; Institute of Pathology, Charité - Universitätsmedizin Berlin (Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Breimer+GE%22">Breimer GE</searchLink>; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rijken+JA%22">Rijken JA</searchLink>; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Devriese+L%22">Devriese L</searchLink>; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Baumeister+P%22">Baumeister P</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität (LMU) Munich University Hospital, Munich, Germany.; Bavarian Center for Cancer Research (BZKF), Munich Partner Site, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Skálová+A%22">Skálová A</searchLink>; Department of Pathology, Charles University, Faculty of Medicine in Plzen, Plzen, Czech Republic.; Bioptic Laboratory, Ltd, Plzen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Schallenberg+S%22">Schallenberg S</searchLink>; Institute of Pathology, Charité - Universitätsmedizin Berlin (Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Klauschen+F%22">Klauschen F</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Center for Neuropathology, Ludwig-Maximilian-University, Munich, Germany.; Bavarian Center for Cancer Research (BZKF), Munich Partner Site, Munich, Germany.; BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Mock+A%22">Mock A</searchLink>; Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU Munich, Munich, Germany.; Division of Translational Medical Oncology, DKFZ & National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2360-2378. <i>Date of Electronic Publication: </i>2026 May 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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