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P450 Cyptide Synthase AscB Catalyzes Fused Cyclophane at the YxWxH Motif on the Precursor Peptides.

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Title: P450 Cyptide Synthase AscB Catalyzes Fused Cyclophane at the YxWxH Motif on the Precursor Peptides.
Authors: Haedar JR; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia., Khan AH; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia., Gullick J; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia., Hansen MH; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia., Coe LJ; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia., De Voss JJ; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia., Romanuks V; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia., Smits G; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.; Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena 3, LV-1048 Riga, Latvia., Donadio S; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.; NAICONS Srl, 20139 Milan, Italy., Cryle MJ; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia., Phan CS; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.
Source: Organic letters [Org Lett] 2026 May 15; Vol. 28 (19), pp. 5966-5971. Date of Electronic Publication: 2026 May 03.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Haedar+JR%22">Haedar JR</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Khan+AH%22">Khan AH</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Gullick+J%22">Gullick J</searchLink>; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Hansen+MH%22">Hansen MH</searchLink>; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Coe+LJ%22">Coe LJ</searchLink>; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22De+Voss+JJ%22">De Voss JJ</searchLink>; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Romanuks+V%22">Romanuks V</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Smits+G%22">Smits G</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.; Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena 3, LV-1048 Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Donadio+S%22">Donadio S</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.; NAICONS Srl, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cryle+MJ%22">Cryle MJ</searchLink>; Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Clayton, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Phan+CS%22">Phan CS</searchLink>; Latvian Institute of Organic Synthesis, Aizkraukles Street 21, LV-1006 Riga, Latvia.
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  Data: <searchLink fieldCode="JN" term="%22100890393%22">Organic letters</searchLink> [Org Lett] 2026 May 15; Vol. 28 (19), pp. 5966-5971. <i>Date of Electronic Publication: </i>2026 May 03.
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        Value: 10.1021/acs.orglett.6c01044
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              Text: 2026 May 15
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