Ubiquitination of DDX21 by HERC2 induces a dormancy-like phenotype via the NUCKS1-p21/p27 axis to promote radio-resistance in colorectal cancer cells.
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| Title: | Ubiquitination of DDX21 by HERC2 induces a dormancy-like phenotype via the NUCKS1-p21/p27 axis to promote radio-resistance in colorectal cancer cells. |
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| Authors: | Xiao Y; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China., He M; Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China., Yao H; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China., Song Y; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China.; Ministry of Education and Training of Children's Hospital Affiliated to Fudan University, Shanghai, China., Hu Y; Department of Pathology, China-Japan Union Hospital of Jilin University, Changchun, China., Liu X; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China., Bai Y; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China., Zhang J; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China., Shao C; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China. clshao@shmu.edu.cn.; Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China. clshao@shmu.edu.cn., Pan Y; Institute of Radiation Medicine, Shanghai Medical College, Fudan University, Shanghai, China. swallowpan@fudan.edu.cn. |
| Source: | Cell death & disease [Cell Death Dis] 2026 May 03; Vol. 17 (1). Date of Electronic Publication: 2026 May 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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