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GCN5L1-Mediated Lysine Acetylation Regulates Mitochondrial Bioenergetics and Redox Homeostasis in the Aged Heart.

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Title: GCN5L1-Mediated Lysine Acetylation Regulates Mitochondrial Bioenergetics and Redox Homeostasis in the Aged Heart.
Authors: Stewart JE; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Islam R; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Meadows E; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Mogus JP; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Department of Physiology, Pharmacology & Toxicology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Velayutham M; In Vivo Multifunctional Magnetic Resonance Center, Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Khramtsov VV; In Vivo Multifunctional Magnetic Resonance Center, Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Scott I; Division of Cardiology, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA., Hollander JM; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Department of Physiology, Pharmacology & Toxicology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Thapa D; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.
Source: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2026 Apr 13; Vol. 15 (4). Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101668981 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3921 (Print) Linking ISSN: 20763921 NLM ISO Abbreviation: Antioxidants (Basel) Subsets: PubMed not MEDLINE
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  Data: GCN5L1-Mediated Lysine Acetylation Regulates Mitochondrial Bioenergetics and Redox Homeostasis in the Aged Heart.
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  Data: <searchLink fieldCode="AU" term="%22Stewart+JE%22">Stewart JE</searchLink>; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Islam+R%22">Islam R</searchLink>; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Meadows+E%22">Meadows E</searchLink>; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Mogus+JP%22">Mogus JP</searchLink>; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Department of Physiology, Pharmacology & Toxicology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Velayutham+M%22">Velayutham M</searchLink>; In Vivo Multifunctional Magnetic Resonance Center, Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Khramtsov+VV%22">Khramtsov VV</searchLink>; In Vivo Multifunctional Magnetic Resonance Center, Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Scott+I%22">Scott I</searchLink>; Division of Cardiology, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA.<br /><searchLink fieldCode="AU" term="%22Hollander+JM%22">Hollander JM</searchLink>; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Department of Physiology, Pharmacology & Toxicology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Thapa+D%22">Thapa D</searchLink>; Division of Exercise Physiology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; Mitochondria, Metabolism & Bioenergetics Working Group, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.
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  Data: <searchLink fieldCode="JN" term="%22101668981%22">Antioxidants (Basel, Switzerland)</searchLink> [Antioxidants (Basel)] 2026 Apr 13; Vol. 15 (4). <i>Date of Electronic Publication: </i>2026 Apr 13.
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        Value: 10.3390/antiox15040481
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              Text: 2026 Apr 13
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