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Evaluation of the Anticancer Effects of Warburgia salutaris Leaf Extracts: A Comparative Study of Both Liposomal-Encapsulated and Unencapsulated Extracts, with Mechanistic Insights into Apoptotic Signalling.

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Title: Evaluation of the Anticancer Effects of Warburgia salutaris Leaf Extracts: A Comparative Study of Both Liposomal-Encapsulated and Unencapsulated Extracts, with Mechanistic Insights into Apoptotic Signalling.
Authors: Tswaledi DM; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Mokgotho MP; Department of Physiology, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Mphahlele MS; Department of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa., Makola RT; Department of Biochemistry and Microbiology, University of Limpopo, Sovenga 0727, South Africa., Ngilirabanga JB; Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Witika BA; Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Mathe EH; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Gololo SS; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Kgopa AH; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa., Shai LJ; Department of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Apr 16; Vol. 27 (8). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Evaluation of the Anticancer Effects of Warburgia salutaris Leaf Extracts: A Comparative Study of Both Liposomal-Encapsulated and Unencapsulated Extracts, with Mechanistic Insights into Apoptotic Signalling.
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  Data: <searchLink fieldCode="AU" term="%22Tswaledi+DM%22">Tswaledi DM</searchLink>; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Mokgotho+MP%22">Mokgotho MP</searchLink>; Department of Physiology, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Mphahlele+MS%22">Mphahlele MS</searchLink>; Department of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa.<br /><searchLink fieldCode="AU" term="%22Makola+RT%22">Makola RT</searchLink>; Department of Biochemistry and Microbiology, University of Limpopo, Sovenga 0727, South Africa.<br /><searchLink fieldCode="AU" term="%22Ngilirabanga+JB%22">Ngilirabanga JB</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Witika+BA%22">Witika BA</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Mathe+EH%22">Mathe EH</searchLink>; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Gololo+SS%22">Gololo SS</searchLink>; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Kgopa+AH%22">Kgopa AH</searchLink>; Department of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.<br /><searchLink fieldCode="AU" term="%22Shai+LJ%22">Shai LJ</searchLink>; Department of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2026 Apr 16; Vol. 27 (8). <i>Date of Electronic Publication: </i>2026 Apr 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101092791 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1422-0067 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214220067%22">14220067 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Sci <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 16
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