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SARS-CoV-2 Effects on Respiratory and Neurological Systems: Morphological Findings and Gene Expression in K18-hACE2 Mice Model.

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Title: SARS-CoV-2 Effects on Respiratory and Neurological Systems: Morphological Findings and Gene Expression in K18-hACE2 Mice Model.
Authors: de Almeida ALT; Laboratory of Viral Morphology and Morphogenesis, Oswaldo Cruz Institute, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., da Silva AMV; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Souza MME; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Rodrigues MPMD; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Coelho FS; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., da Rosa LC; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Azamor T; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Várady CBS; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., da Silva BJD; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., de Almeida AC; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Santos RT; Laboratory of Virological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Müller R; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Gonçalves RB; Department of Biochemistry, Biomedical Institute, Federal University of the State of Rio de Janeiro, Rio de Janeiro 20211-040, RJ, Brazil., Ano Bom APD; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Barreto-Vieira DF; Laboratory of Viral Morphology and Morphogenesis, Oswaldo Cruz Institute, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.
Source: Microorganisms [Microorganisms] 2026 Apr 10; Vol. 14 (4). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: SARS-CoV-2 Effects on Respiratory and Neurological Systems: Morphological Findings and Gene Expression in K18-hACE2 Mice Model.
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  Data: <searchLink fieldCode="AU" term="%22de+Almeida+ALT%22">de Almeida ALT</searchLink>; Laboratory of Viral Morphology and Morphogenesis, Oswaldo Cruz Institute, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+AMV%22">da Silva AMV</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Souza+MME%22">Souza MME</searchLink>; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+MPMD%22">Rodrigues MPMD</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Coelho+FS%22">Coelho FS</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Rosa+LC%22">da Rosa LC</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Azamor+T%22">Azamor T</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Várady+CBS%22">Várady CBS</searchLink>; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+BJD%22">da Silva BJD</searchLink>; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Almeida+AC%22">de Almeida AC</searchLink>; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+RT%22">Santos RT</searchLink>; Laboratory of Virological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Müller+R%22">Müller R</searchLink>; Laboratory of Preclinical Trials, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Gonçalves+RB%22">Gonçalves RB</searchLink>; Department of Biochemistry, Biomedical Institute, Federal University of the State of Rio de Janeiro, Rio de Janeiro 20211-040, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Ano+Bom+APD%22">Ano Bom APD</searchLink>; Laboratory of Immunological Technology, Department of Experimental and Preclinical Development, Bio-Manguinhos, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Barreto-Vieira+DF%22">Barreto-Vieira DF</searchLink>; Laboratory of Viral Morphology and Morphogenesis, Oswaldo Cruz Institute, Oswaldo Cruz Foundation-Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101625893%22">Microorganisms</searchLink> [Microorganisms] 2026 Apr 10; Vol. 14 (4). <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101625893 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2076-2607 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220762607%22">20762607 </searchLink><i>NLM ISO Abbreviation: </i>Microorganisms <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/microorganisms14040852
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        Text: English
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