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Blood DNA methylation signature of cognitive reserve moderates the association between CSF tau pathology and memory in prodromal Alzheimer's disease.

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Title: Blood DNA methylation signature of cognitive reserve moderates the association between CSF tau pathology and memory in prodromal Alzheimer's disease.
Authors: Lukacsovich D; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA., Young JI; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA., Gomez L; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA., Kunkle BW; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA., Mao Z; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA., Zhang W; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA., Chen XS; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.; Sylvester Comprehensive Cancer Center Miller School of Medicine University of Miami Miami Florida USA., O'Shea DM; Department of Neurology University of Miami Miller School of Medicine Miami Florida USA., Rundek T; Department of Neurology University of Miami Miller School of Medicine Miami Florida USA.; Evelyn F. McKnight Brain Institute University of Miami School of Medicine Miami Florida USA., Martin ER; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA., Wang L; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.; Sylvester Comprehensive Cancer Center Miller School of Medicine University of Miami Miami Florida USA.; Evelyn F. McKnight Brain Institute University of Miami School of Medicine Miami Florida USA.
Corporate Authors: Alzheimer's Disease Neuroimaging Initiative
Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2026 May 01; Vol. 12, pp. e70257. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Blood DNA methylation signature of cognitive reserve moderates the association between CSF tau pathology and memory in prodromal Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Lukacsovich+D%22">Lukacsovich D</searchLink>; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Young+JI%22">Young JI</searchLink>; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Gomez+L%22">Gomez L</searchLink>; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Kunkle+BW%22">Kunkle BW</searchLink>; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Mao+Z%22">Mao Z</searchLink>; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Chen+XS%22">Chen XS</searchLink>; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.; Sylvester Comprehensive Cancer Center Miller School of Medicine University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22O'Shea+DM%22">O'Shea DM</searchLink>; Department of Neurology University of Miami Miller School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Rundek+T%22">Rundek T</searchLink>; Department of Neurology University of Miami Miller School of Medicine Miami Florida USA.; Evelyn F. McKnight Brain Institute University of Miami School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Martin+ER%22">Martin ER</searchLink>; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Division of Biostatistics Department of Public Health Sciences Miller School of Medicine University of Miami Miami Florida USA.; Dr. John T Macdonald Foundation Department of Human Genetics Miller School of Medicine University of Miami Miami Florida USA.; John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami Florida USA.; Sylvester Comprehensive Cancer Center Miller School of Medicine University of Miami Miami Florida USA.; Evelyn F. McKnight Brain Institute University of Miami School of Medicine Miami Florida USA.
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        Value: 10.1002/trc2.70257
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